Fluid-structure interaction analysis of amniotic fluid with fetus and placenta inside uterus exposed to military blasts

Arias, Jonathan; Kurgansky, Gregory; Ong, Chi Wei; Chan-Akeley, Rosalyn; Toma, Milan

doi:10.1016/j.injury.2023.110843

Cited by 2 publications

(1 citation statement)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…One among these datasets was employed as a fixed standard for skull acceleration within the model used (Figure 2). After this step, calculations concerning fluid movement along with boundary interaction were resolved using IMPETUS Afea Solver employing smoothed-particle hydrodynamics (SPH) for fluid domain computations and high-order finite element method to solve solid-domain problems [21].…”

Section: Boundary and Initial Conditionsmentioning

confidence: 99%

Understanding Traumatic Brain Injuries in Military Personnel: Investigating the Dynamic Interplay of the Cerebrospinal Fluid and Brain During Blasts

Frankini,

Basile,

Syed

et al. 2023

Cureus

Self Cite

View full text Add to dashboard Cite

BackgroundIt is estimated that around 450,000 traumatic brain injury cases have occurred in the 21st century with possible under-reporting. Computational simulations are increasingly used to study the pathophysiology of traumatic brain injuries among US military personnel. This approach allows for investigation without ethical concerns surrounding live subject testing. MethodologyThe pertinent data on head acceleration is applied to a detailed 3D model of a patient-specific head, which encompasses all significant components of the brain and its surrounding fluid. The use of finite element analysis and smoothed-particle hydrodynamics serves to replicate the interaction between these elements during discharge through simulation of their fluid-structure dynamics. ResultsThe stress levels of the brain are assessed at varying time intervals subsequent to the explosion. The regions where there is an intersection between the skull and brain are observed, along with the predominant orientations in which displacement of the brain occurs resulting in a brain injury. ConclusionsIt has been determined that the cerebrospinal fluid is inadequate in preventing brain damage caused by multiple abrupt directional shifts of the head. Accordingly, additional research must be undertaken to enhance our comprehension of the injury mechanisms linked with consecutive changes in acceleration impacting the head.

show abstract

Section: Boundary and Initial Conditionsmentioning

confidence: 99%

Understanding Traumatic Brain Injuries in Military Personnel: Investigating the Dynamic Interplay of the Cerebrospinal Fluid and Brain During Blasts

Frankini,

Basile,

Syed

et al. 2023

Cureus

Self Cite

View full text Add to dashboard Cite

show abstract

Post-Trauma Fetal Care Using Computational Analysis in Prenatal Surgical Guidance

Ashkezari,

Bekbolatova,

Mayer

et al. 2024

Surgeries

View full text Add to dashboard Cite

The purpose of this research is to explore the biomechanical consequences of maternal injuries on fetal movements. Additionally, the research aims to comprehend the relationship between these injuries and fetal movement within the amniotic sac and to understand the extent to which the amniotic fluid can provide protection during severe injuries. The focus is on the potential impact these injuries could have on surgical procedures and preventative strategies. Using advanced computational simulations, the study investigates how various maternal injuries can influence the behavior of amniotic fluid and the subsequent stress exerted on fetal development. The findings suggest that maternal injuries can induce stress, primarily affecting the posterior regions of the fetus and the umbilical cord, depending on the boundary and initial conditions. This stress is associated with fetal displacement within the amniotic sac. While the amniotic fluid provides a certain level of protection, its limitations become apparent during severe injuries. These insights have implications for the field of surgery, particularly fetal procedures. They underscore the need for improved protective measures and the development of personalized obstetric and neonatal care strategies. Moreover, the study highlights the potential of computational simulations in aiding surgeons. These simulations can provide a more accurate understanding of the critical areas to focus on during surgical procedures, thereby enhancing the precision and safety of these operations.

show abstract

Fluid-structure interaction analysis of amniotic fluid with fetus and placenta inside uterus exposed to military blasts

Cited by 2 publications

References 29 publications

Understanding Traumatic Brain Injuries in Military Personnel: Investigating the Dynamic Interplay of the Cerebrospinal Fluid and Brain During Blasts

Understanding Traumatic Brain Injuries in Military Personnel: Investigating the Dynamic Interplay of the Cerebrospinal Fluid and Brain During Blasts

Post-Trauma Fetal Care Using Computational Analysis in Prenatal Surgical Guidance

Contact Info

Product

Resources

About