Fluid-structure interaction of heart valve dynamics in comparison to finite-element analysis

Borowski, Finja; Saemann, Michael; Pfensig, Sylvia; Wüstenhagen, Carolin; Ott, R.; Kaule, Sebastian; Siewert, Stefan; Grabow, Niels; Schmitz, Klaus‐Peter; Stiehm, Michael

doi:10.1515/cdbme-2018-0063

Cited by 6 publications

(4 citation statements)

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“…Multiple approaches have been applied to the research of FSI analysis technology, including ALE (Nguyen et al, 2011;Cao, 2016;Borowski et al, 2018), "operator split" Lagrangian-Euler method (Luraghi et al, 2019;Pasta et al, 2020), the immersed boundary method (IBM) (Lemmon and Yoganathan, 2000;Jendoubi et al, 2014;Kallemov et al, 2016), and the curvilinear immersed boundary (CURVIB) method (Ge and Sotiropoulos, 2007;Borazjani et al, 2008). Each of these technical methods have their own specific characteristics.…”

Section: Discussionmentioning

confidence: 99%

Fluid-Structure Interaction Analysis on the Influence of the Aortic Valve Stent Leaflet Structure in Hemodynamics

et al. 2022

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Transcatheter aortic valve replacement (TAVR) is a minimally invasive surgical treatment for heart valve disease. At present, personalized TAVR valves are not available for some patients. This study adopts the fluid-structure interaction (FSI) model of the research object that has a three-disc leaflet form and structural design in the valve leaflet area. The valve opening shape, orifice area, stress-strain, and distribution of hemodynamic flow and pressure were compared under the condition of equal contact area between valve and blood. The FSI method was used to simulate the complex three dimensional characteristics of the flow field more accurately around the valve after TAVR stent implantation. Three personalized stent systems were established to study the performance of the leaflet design based on computational fluid dynamics. By comparing the different leaflet geometries, the maximum stress on leaflets and stents of model B was relatively reduced, which effectively improved the reliability of the stent design. Such valve design also causes the opening area of the valve leaflet to increase and the low-velocity area of the flow field to decrease during the working process of the valve, thus reducing the possibility of thrombosis. These findings can underpin breakthroughs in product design, and provide important theoretical support and technical guidance for clinical research.

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Section: Discussionmentioning

confidence: 99%

Fluid-Structure Interaction Analysis on the Influence of the Aortic Valve Stent Leaflet Structure in Hemodynamics

et al. 2022

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“…Therefore, the geometric resolution λ of deformation depends on the image measurement accuracy σ and the GSD. Equation (1) shows this relationship, whereby the introduced factor is based on GUM [62].…”

Section: Characteristic Of Fsi-systemmentioning

confidence: 99%

“…The interaction between a fluid and a flexible structure is a common physical phenomenon in nature. An example is the interaction of a heart valve with the surrounding blood, where different pressure distributions change the shape and position of the valve [1]. The interaction is bidirectional in other examples, such as flapping owl wings or wind turbines [2,3].…”

Section: Introductionmentioning

confidence: 99%

A Wind Tunnel Setup for Fluid-Structure Interaction Measurements Using Optical Methods

Nietiedt

Wester

Langidis

et al. 2022

Sensors

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The design of rotor blades is based on information about aerodynamic phenomena. An important one is fluid-structure interaction (FSI) which describes the interaction between a flexible object (rotor blade) and the surrounding fluid (wind). However, the acquisition of FSI is complex, and only a few practical concepts are known. This paper presents a measurement setup to acquire real information about the FSI of rotating wind turbines in wind tunnel experiments. The setup consists of two optical measurement systems to simultaneously record fluid (PIV system) and deformation (photogrammetry system) information in one global coordinate system. Techniques to combine both systems temporally and spatially are discussed in this paper. Furthermore, the successful application is shown by several experiments. Here, different wind conditions are applied. The experiments show that the new setup can acquire high-quality area-based information about fluid and deformation.

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“…A linear elastic behavior was assumed for leaflet material properties (Young modulus: 10 MPa, Poisson ratio: 0.46 and leaflet material density: 1000 kg/m 3 ) and blood was specified as a homogeneous, Newtonian and incompressible fluid (fluid density: 1060 kg/m 3 and dynamic viscosity: 0.0035 Pa s) [17]. In a further step, the geometrical configuration as well as the flow field of the FSI-modeled valve prosthesis was used for RT simulation in a quasi-steady state manner.…”

Section: Fluid-structure Interactionmentioning

confidence: 99%

Computational flow analysis of the washout of an aortic valve by means of Eulerian transport equation

Stiehm

Borowski

Kaule

et al. 2019

Current Directions in Biomedical Engineering

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Although the development of the transcatheter aortic valve (TAV) has saved many lives of inoperable patients and has a very good clinical outcome, concerns about valve thrombosis are increasing. Due to the potential risk of late clinically relevant events, the US Food and Drug Administration (FDA) suggests a careful systematic investigation of thrombosis and reduced leaflet motion related to hemodynamic changes induced by TAV implantation. Furthermore, recently published position papers of the ISO working group address numerical and experimental flow field assessment of TAV. In particular, pathologically high shear rates and a reduced washout of the sinuses may increase the risk of valve thrombosis and should therefore be investigated. By means of fluid-structure interaction (FSI) as a powerful in silico tool, the transient flow field in an aortic valve was analyzed. A linear elastic behavior was assumed for leaflet material properties (Young modulus: 10 MPa, Poisson ratio: 0.46 and leaflet material density: 1000 kg/m3) and blood was specified as a homogeneous, Newtonian and incompressible fluid (fluid density: 1060 kg/m3 and a dynamic viscosity: 0.0035 Pa s). In this numerical study we present a Eulerian approach, which is based on transport equation of the residence time (RT) as a passively transported scalar. It can be clearly seen that the RT is significantly higher in the sinus referred to the main flow. At time step t = 0.25 s, the average residence time in the main flow is RTavg ≈ 0.05 s, whereas RT ≈ 0.25 s in the sinus. In particular, RT is a valuable hemodynamic metric to quantify the washout of the sinus in order to evaluate the thrombogenic potential of TAV devices. Further studies will concentrate on particle image velocimetry measurements for validation purposes. In particular the velocity in the sinus and therefore the washout is one important hemodynamic key feature that has to be improved for future TAV designs.

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Fluid-structure interaction of heart valve dynamics in comparison to finite-element analysis

Cited by 6 publications

References 0 publications

Fluid-Structure Interaction Analysis on the Influence of the Aortic Valve Stent Leaflet Structure in Hemodynamics

Fluid-Structure Interaction Analysis on the Influence of the Aortic Valve Stent Leaflet Structure in Hemodynamics

A Wind Tunnel Setup for Fluid-Structure Interaction Measurements Using Optical Methods

Computational flow analysis of the washout of an aortic valve by means of Eulerian transport equation

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