Fluidic logic element sample switch for correlation chromatography

Annino, Raymond; Gonnord, M. F.; Guiochon, Georges

doi:10.1021/ac50039a014

Search citation statements

Order By: Relevance

Paper Sections

Select...

Introduction2

The Multiplex and Throughput Advantages1

Citation Types

Supporting

Mentioning

Contrasting

Unclassified

Year Published

1980

2015

Publication Types

Select...

Article8

Relationship

Self Cite0

Independent8

Authors

Journals

Cited by 51 publications

(17 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…An example of the dramatic im provement in signal-to-noise ratio made possible by the throughput ad vantage is contained in Figure 6 of ref erence (20).…”

Section: The Multiplex and Throughput Advantagesmentioning

confidence: 99%

Report

1980

Anal. Chem.

View full text Add to dashboard Cite

show abstract

“…An example of the dramatic im provement in signal-to-noise ratio made possible by the throughput ad vantage is contained in Figure 6 of ref erence (20).…”

Section: The Multiplex and Throughput Advantagesmentioning

confidence: 99%

Report

1980

Anal. Chem.

View full text Add to dashboard Cite

show abstract

“…The implementation of multiplexing based on pseudo-random binary modulation sequences allows circumventing this limitation. The first realization of this principle in chromatography was demonstrated in correlation chromatography [23][24][25][26][27][28]. Multiplexing utilizing Hadamard encoding has been applied to increase S/N in many fields, including TOF-MS [29][30][31], CE [32][33][34][35][36], and GC-MS [37][38][39][40].…”

Section: Introductionmentioning

confidence: 99%

Implementation of Hadamard encoding for rapid multisample analysis in liquid chromatography

Siegle

Trapp

2015

J. Sep. Science

View full text Add to dashboard Cite

Multiplexing based on pseudo-binary modulation sequences is known to increase the signal-to-noise ratio. In this work, Hadamard transform multiplexing is used in high-performance liquid chromatography to increase the sample throughput. Using structured modulation sequences to encode and control sample injections in combination with a fitting algorithm to deconvolute the complex data allowed us to evaluate convoluted chromatograms of up to 128 samples containing three and five analytes, respectively, with good accuracy (<2% deviation). In comparison to conventional high-performance liquid chromatography the analysis time could be reduced by 30 and 55%, respectively.

show abstract

“…The chromatogram is then recovered by computational deconvolution of the resulting signal 111. Several types of devices have been constructed which modulate the sample stream producing multiple concentration pulses [2,3,4,5,6]. These devices modulate most or all components of the sample.…”

Section: Introductionmentioning

confidence: 99%