Flumazenil in treatment benzodiazepine withdrawal syndrome: Case report

Ramah, Aleksandar; Todorovic, Mirjana; Crnic, Katarina

doi:10.5937/hpimj1502261r

Cited by 1 publication

(1 citation statement)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Th e assessing these factors for each patient is a signifi cant part of the therapeutic process, followed by appropriate therapeutic actions, which includes the elements of the psychotherapeutic and social therapeutic approaches, in order to support the results of the pharmacotherapy treatment and as much as possible reduce the risk of relapse [23]. It is emphasized that opiate dependence aff ects the whole person, both the biochemistry of her brain, and her psychological and social functioning.…”

Section: Discussionmentioning

confidence: 99%

Recidivism with opiate addicted patients on buprenorphine substitution treatment: Case report

Crnic¹,

Todorovic²

2017

Hosp Pharm Int Multi J

Self Cite

View full text Add to dashboard Cite

SUMMARYIntroduction: Opiate dependence is a serious, chronic and recurrent psychiatric disorder, whose prevalence reach epidemic proportions. This also contributes to a signifi cant increase in mortality, associated with overdose with opiates, as well as the rise in other health and social problems of the society. The methods and availability of treatment do not correspond to increased treatment needs, and treatment success is limited by the characteristics of the disorder, or numerous risk factors, which contribute to a high percentage of recidivism. Good clinical practice guidelines have defi ned treatment recommendations that include high and low-demanding programs. The personalized and integrative approaches are emphasized. Case report: The patient aged 41 years, intravenous-use opiate addict from his adolescences, with numerous psychological, health and social complications of addiction, is a participant in institutional treatment, following a court order as a measure of obligatory treatment, due to criminal off enses related to addiction. The history of the disease refers to numerous unsuccessful attempts to heal and short-term abstinence in the past, mainly in penal institutions. The patient meets all the criteria defi ned by the guidelines for inclusion in the buprenorphine maintenance program started in the year 2013. During the four-year treatment, the doses of the drug were adapted as needed; two heroin relapses and many in-risk situations for relapse were registered. The treatment continuated with close monitoring of the patient's condition and, with appropriate psychosocial interventions, contribute to keeping the patient in treatment and preventing the development of new complications of addiction, as well an improving the quality of his life. Discussion: Pharmacological treatment of opioid dependence relies on agents belonging to groups of antagonists, agonists and partial agonists of opiate receptors. The earlier programs with abstinence as a treatment goal have signifi cantly allocated the place to "harm reduction" programs, where the therapeutic goals are less demanding and defi ned as the harm-reduction of opiate dependence on the individual and the society. Treatment guidelines defi ne the principles and types of treatment regimens with agonists and partial agonists of opiate receptors and most commonly used are methadone and buprenorphine. The high risk of relapses despite treatment is defi ned and a comprehensive approaches and inclusion of Cognitive Behavior Therapy /CBT/, family and social therapy are needed.

show abstract

Section: Discussionmentioning

confidence: 99%