2003
DOI: 10.1038/sj.eye.6700361
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Fluorescein angiography and patchy skin discoloration: a case report

Abstract: The survival rate of cutaneous melanoma is related to the histological type of tumour and the depth of dermal invasion of the original lesion. 10 In this case, the primary cutaneous melanoma was spindle cell type with a depth of 10 mm. The prognosis is poor 11,12 due to disseminated disease and the poor response to chemotherapeutic regimes. However, the behaviour of melanoma is unpredictable and at times quiescent, resulting in long survival after initial diagnosis and even first onset of metastatic disease a… Show more

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Cited by 11 publications
(9 citation statements)
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“…[5][6][7][8][9][10] However, complications after angiography have been reported, including mild nausea, vomiting, skin discoloration and severe anaphylactic shock. 19,20 With non-invasive OCT, CME following uveitis or post-cataract surgery can be detected. The quality and sensitivity of OCT images are at least as good as angiography; however, OCT has fewer complications.…”
Section: Sixmentioning
confidence: 99%
“…[5][6][7][8][9][10] However, complications after angiography have been reported, including mild nausea, vomiting, skin discoloration and severe anaphylactic shock. 19,20 With non-invasive OCT, CME following uveitis or post-cataract surgery can be detected. The quality and sensitivity of OCT images are at least as good as angiography; however, OCT has fewer complications.…”
Section: Sixmentioning
confidence: 99%
“…43,44 Patients also experience dizziness, headache, diarrhea, convulsions with bradycardia, circulatory problems, irritation at the injection site, vasovagal episodes (fainting), pruritus (itchy), urticaria (in 0.5% of patients with reactions), myocardial infarction, breathlessness, extravasation, thrombophlebitis (infl ammation of a clot in the superfi cial venous system), local tissue necrosis, laryngeal and facial edema, bronchospasm, and anaphylaxis and allergic reactions (in 0.5-1% of total patients). [43][44][45][46][47][48] The primary route of excretion is the kidney. 38 Cardiac arrest and death are very rare; the mortality rate is 0.0005%.…”
Section: Fluoresceinmentioning
confidence: 99%
“…Apesar de ser considerada segura, inúmeras complicações relacionadas à injeção de fluoresceína intravenosa já foram relatadas na literatura (2)(3)(4)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23) . Com o intuito de evitá-las vários estudos foram realizados comparando a ocorrência de reações adversas e alterações laboratoriais entre diferentes concentrações de fluoresceína sódica, porém na maioria dos trabalhos a dosagem injetada foi praticamente a mesma, de 500 mg (4,9,13,19,22) .…”
Section: Discussionunclassified