Fluorescein sodium use during spinal ependymoma resection

Sun, Zhenxing; Yuan, Dan; Sun, Yaxing; Zhang, Zhanquan; Wang, James; Guo, Yi; Wang, Guoqin; Liu, Dongkang; Chen, Peng; Jing, Linyuan; Yang, Fusheng; Zhang, Peihai; Zhang, Huifang; Wu, Youtu; Wei, Shi; Wang, Guihuai

doi:10.18679/cn11-6030/r.2017.021

Cited by 2 publications

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“…Sun et al reported that SF could help in detecting areas of pathological neoangiogenesis during surgery, for example in tumor infiltration and metastasis. However, it requires a combination of white and yellow light for detection of the areas of the tumor that are not visible with SF [ 10 ].…”

Section: Discussionmentioning

confidence: 99%

5-aminolevulinic acid and sodium fluorescein in IV ventricle ependymoma surgery: preliminary experience comparing the two techniques

et al. 2022

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Purpose The aim of this study is to compare the use of 5-aminolevulinic acid (5-ALA) and sodium fluorescein (SF) in IV ventricular ependymoma (IVEP) surgical resection. Methods In this retrospective study, six patients with IVEP were enrolled. Gender ratio 2:1 male to female, with mean age 38.9 years old. A 5-ALA oral dose of 20 mg/kg and a SF intravenous dose of 2 mg/kg were administered. Telo-velar approach, operative microscope, and intraoperative monitoring were used in all the operations. We retrospectively compared the two fluorescence techniques at four steps during the surgical procedure: step 1: exposure of the tumor; step 2: dissection of the lesion from the cerebellum; step 3: assessment of the tumor borders and differentiation from normal tissue at the base of implants; and step 4: evaluation of possible residual tissue in the surgical cavity. Results At the first step, the ependymomas resulted well delineated by both fluorescent agents. In this step, 5-ALA was particularly helpful in the case of recurrent ependymoma. At step 2, 5-ALA provided a better identification of the ependymoma boundaries and distinction from cerebellum hemispheres than SF. In steps 3 and 4, SF was really helpful to detect tumor tissue. Conclusion According to our experience, fluorescence-guided surgery of IVEP with 5-ALA and SF is useful to maximize surgical resection with less risk of brainstem injury. Both fluorescence techniques are helpful in different steps of IVEP resection. However, further studies are needed to confirm our preliminary data.

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Section: Discussionmentioning

confidence: 99%

5-aminolevulinic acid and sodium fluorescein in IV ventricle ependymoma surgery: preliminary experience comparing the two techniques

et al. 2022

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“…Therefore, It is clearly pointed out in China's 11th Five-Year Plan that "scarce resources should be rationally utilized, strategic reserve resources and precious resources should be protected, and wastes with potential for resource utilization should be comprehensively recycled [4] . In recent years, studies on the extraction of highvalue elements from fly ash have gradually increased [5]- [6] , and breakthroughs have been made in the extraction of aluminum, lithium, gallium and other elements [7]- [8] . Many scholars have also carried out a lot of studies on the extraction of rare earth from coal and fly ash.…”

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Study on factors affecting rare earth leaching rate in acid leaching process of fly ash

2022

JTAS

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There is a large amount of enrichment of rare earth elements in Zhungeer coal and coal ash, making it possible to use fly ash as a source for industrial production of rare earth elements. In order to optimize the leaching process of rare earth elements in fly ash and increase the leaching rate, the circulating fluidized bed fly ash of Zhungeer Power Plant was used as the material, and the single factor test and orthogonal test were used to influence the leaching rate of rare earth elements in the acid leaching process of fly ash The factors were discussed, and the results showed that when fly ash and 3mol/L hydrochloric acid were leached at a ratio of 1:10 for 2h at 130 0C, the element leaching effect was the best, and the leaching rate could reach 97%.

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Fluorescein sodium use during spinal ependymoma resection

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Cited by 2 publications

References 13 publications

5-aminolevulinic acid and sodium fluorescein in IV ventricle ependymoma surgery: preliminary experience comparing the two techniques

5-aminolevulinic acid and sodium fluorescein in IV ventricle ependymoma surgery: preliminary experience comparing the two techniques

Study on factors affecting rare earth leaching rate in acid leaching process of fly ash

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