Fluorescence-based detection of nitric oxide in aqueous and methanol media using a copper(ii) complex

Abstract

The quenched fluorescent intensity of a copper(II) complex, 1, of a fluorescent ligand, in degassed methanol or aqueous (buffered at pH 7.2) solution, was found to reappear on exposure to nitric oxide. Thus, it can function as a fluorescence based nitric oxide sensor. It has been found that the present complex can be used to sense nanomolar quantities of nitric oxide in both methanol and pH 7.2 buffered-water medium.

Nickel(II) Dithiocarbamate Complexes Containing Sulforhodamine B as Fluorescent Probes for Selective Detection of Nitrogen Dioxide

“…Most fluorescent probes reported are for nitric oxide (NO) detection. While transition metal complex based probes contain the nitric oxide reactive metal as fluorescence quencher, 6-10 the organic dye based probes detect nitric oxide indirectly through oxidation of aromatic amines by N 2 O 3 , 11-12 , which is produced via oxidation of NO by O 2 . 13-14 We herein report the first fluorescent probe for selective detection of nitrogen dioxide, containing Ni(II) as a fluorescence quencher and NO 2 reaction center.…”

Regenerative fluorescence “turn-on” probe for biothiols through Cu(II)/Cu(I) redox conversion

“…Cu II L was crystallized as a dimer by slow evaporation of diethyl ether into a methanol/water solution of Cu II L. The strong reduction in fluorescence of Cu II L was likely due to the paramagnetic character of Cu(II) alone [25][26][27][28]: Fluorescence quenching takes places through photoinduced electron transfer from the coumarin singlet excited state to the bound Cu(II) ion.…”

Carbazole–azine based fluorescence ‘off–on’ sensor for selective detection of Cu2+ and its live cell imaging

“…In these sensors, the mechanism involves opening of the spirolactam ring upon binding with a Cu 2+ ion, resulting in fluorescence enhancement. In addition, several other chemosensors have been reported with different signaling mechanisms for the optical detection of paramagnetic ions based on photo‐induced electron transfer, metal–ligand charge transfer, intramolecular charge transfer (ICT), excimer/exciplex formation, and excited‐state intermolecular proton transfer …”