2015
DOI: 10.1063/1.4938025
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Fluorescence enhancement in large-scale self-assembled gold nanoparticle double arrays

Abstract: Localized surface plasmon resonances excited in metallic nanoparticles confine and enhance electromagnetic fields at the nanoscale. This is particularly pronounced in dimers made from two closely spaced nanoparticles. When quantum emitters, such as dyes, are placed in the gap of those dimers, their absorption and emission characteristics can be modified. Both processes have to be considered when aiming to enhance the fluorescence from the quantum emitters. This is particularly challenging for dimers, since the… Show more

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Cited by 18 publications
(17 citation statements)
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References 70 publications
(149 reference statements)
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“…For application design, this work contained the analytical features (compared with previous reports) use) in clinics, selection of specific biomarkers (cTnI and CK-MB), and low sample consumption in high speed (10 μL of serum for 30 min reaction). In addition, our plasmonic gold nano-island platform afforded enhancement factors of~130-fold, compared with the typical literatures 58,59 with optimized enhancement factors of 50-fold and 99-fold using plasmonic gold nanoparticles. Therefore, our approach addressed the application needs and technical challenges from a clinical perspective, different from typical literatures 58,59 on sensing mechanism and device structure using plasmonic nanostructures to enhance the fluorescence of dyes from pure chemical/physical perspective.…”
Section: Resultsmentioning
confidence: 86%
“…For application design, this work contained the analytical features (compared with previous reports) use) in clinics, selection of specific biomarkers (cTnI and CK-MB), and low sample consumption in high speed (10 μL of serum for 30 min reaction). In addition, our plasmonic gold nano-island platform afforded enhancement factors of~130-fold, compared with the typical literatures 58,59 with optimized enhancement factors of 50-fold and 99-fold using plasmonic gold nanoparticles. Therefore, our approach addressed the application needs and technical challenges from a clinical perspective, different from typical literatures 58,59 on sensing mechanism and device structure using plasmonic nanostructures to enhance the fluorescence of dyes from pure chemical/physical perspective.…”
Section: Resultsmentioning
confidence: 86%
“…6f). The performance comparison of the fabricated LSPR biosensor performance comparison between the present HA detection biosensor and other biosensors reported is summarized in Table 1 [29]. Thus, the proposed LSPR biosensor can successfully detected the HA protein in clinical samples with high selectivity.…”
Section: Methodsmentioning
confidence: 88%
“…To increase the LSPR enhancement effect, FAM dye was introduced. Moreover, the LSPR enhancement effect by fluorescence dye needs to adequate distance between fluorophore and nanoparticle surface [29,30]. The FAM-tagged DNA 3 W J showed the high rigidity and provide the defined distance around 5-6 nm between FAM and hAuSN surface for making LSPR effect.…”
Section: Introductionmentioning
confidence: 99%
“…By analysing this dependence, it is possible to determine the impact of changes in nanoparticle sizes on their optical and electrical properties. For this purpose it would be very interesting to study the optical properties of nanocomposites with matrices that fall far beyond the band of the absorption and luminescence spectra of nanoparticles (Flessau et al, 2014;Chekini et al, 2015;Chernozatonskiy et al, 2018).…”
Section: Introductionmentioning
confidence: 99%