Fluorescence Spectrum Characteristics of Gold Nanorods

An interesting nanodrug delivery system is polyelectrolyte multilayer-coated nanogold. For better understanding of the binding of polycations or the counter-indicative deposition of polyanions on the citrate-stabilized gold nanoparticles, we used a surface-enhanced Raman spectroscopy to characterize the orientation of the polyions towards the gold surface. It was found that poly-allylamine replaces citrate molecules while the polyanion, poly-styrene sulfonate, intercalates in the citrate shell. One of the major obstacles for polyelectrolyte-coated nanogold is its tendency to agglomerate in the presence of high ion concentration as present, e.g., in blood. A novel encapsulation protocol for polyelectrolyte multilayer coating of gold nanoparticles was developed to successfully overcome this drawback. Moreover, electrostatic functionalization of the polyelectrolyte shell with a model target molecule for cancer, folic acid, induced a significant increase in the particle uptake in folate-receptor over-expressing breast cancer cell lines, VP 229 and MDA MB 231, compared to non-targeted particles or cells (non-activated macrophages) not expressing the folate receptor

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Synthesis and multidisciplinary characterization of polyelectrolyte multilayer-coated nanogold with improved stability toward aggregation

Mandal

Bonifacio

Zanuttin

et al. 2010

Colloid Polym Sci

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Effect of thickness on the optical nonlinearity of gold colloidal nanoparticles prepared by laser ablation

Golian

Dorranian

2013

Opt Quant Electron

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Optical properties of Au nanoparticles coated on surface of glass or anodic aluminum oxide template

Feng

et al. 2012

J. Wuhan Univ. Technol.-Mat. Sci. Edit.

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Fluorescence Spectrum Characteristics of Gold Nanorods

Cited by 18 publications

References 10 publications

Synthesis and multidisciplinary characterization of polyelectrolyte multilayer-coated nanogold with improved stability toward aggregation

Synthesis and multidisciplinary characterization of polyelectrolyte multilayer-coated nanogold with improved stability toward aggregation

Effect of thickness on the optical nonlinearity of gold colloidal nanoparticles prepared by laser ablation

Optical properties of Au nanoparticles coated on surface of glass or anodic aluminum oxide template

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