Fluorescent AgInS/ZnS quantum dots microplate and lateral flow immunoassays for folic acid determination in juice samples

Novikovа, A. S.; Ponomaryova, Тatiana S.; Goryacheva, Irina Yu.

doi:10.1007/s00604-020-04398-1

Cited by 20 publications

(8 citation statements)

References 39 publications

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“…For instance, in rather high demand are highly sensitive and inexpensive test systems for assaying the quality of foodstuffs, which would make it possible to assess the content of biologically active substances within minutes. An express test developed for the detection of folic acid with a visual assessment of the results using quantum dots is described in [79]. Moreover, the authors gave up on Cd-based quantum dots, which are the most popular for similar purposes owing to their potential toxicity, and used hydrophilic photostable AgInS/ZnS nanocrystals.…”

Section: Optical Methods Of Immunodetection Based On Nanomaterialsmentioning

confidence: 99%

“…Figure 4 summarizes the application data and the various types of nanoparticle modifications described below. [74], Pt-nanoflower-type NPs [75], Au@PTNps [76], Au@Ag-PtNPs [77], quantum dots [78][79][80], magnetic beads [81].…”

Section: Immunodiagnostic Systems Based On Nanomaterialsmentioning

confidence: 99%

“…Figure 4. Useful modifications of nanoparticles for improvement of the analyte detection described in this review: AuNPs[65][66][67][68][69][70][71][72][73], Superspherical AuNPs[74], Pt-nanoflower-type NPs[75], Au@PTNps[76], Au@Ag-PtNPs[77], quantum dots[78][79][80], magnetic beads[81].…”

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confidence: 99%

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Antibodies as Biosensors’ Key Components: State-of-the-Art in Russia 2020–2021

Rudenko

Fursova

Shepelyakovskaya

et al. 2021

Sensors

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The recognition of biomolecules is crucial in key areas such as the timely diagnosis of somatic and infectious diseases, food quality control, and environmental monitoring. This determines the need to develop highly sensitive display devices based on the achievements of modern science and technology, characterized by high selectivity, high speed, low cost, availability, and small size. Such requirements are met by biosensor systems—devices for reagent-free analysis of compounds that consist of a biologically sensitive element (receptor), a transducer, and a working solution. The diversity of biological material and methods for its immobilization on the surface or in the volume of the transducer and the use of nanotechnologies have led to the appearance of an avalanche-like number of different biosensors, which, depending on the type of biologically sensitive element, can be divided into three groups: enzyme, affinity, and cellular/tissue. Affinity biosensors are one of the rapidly developing areas in immunoassay, where the key point is to register the formation of an antigen–antibody complex. This review analyzes the latest work by Russian researchers concerning the production of molecules used in various immunoassay formats as well as new fundamental scientific data obtained as a result of their use.

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Section: Optical Methods Of Immunodetection Based On Nanomaterialsmentioning

confidence: 99%

Section: Immunodiagnostic Systems Based On Nanomaterialsmentioning

confidence: 99%

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Antibodies as Biosensors’ Key Components: State-of-the-Art in Russia 2020–2021

Rudenko

Fursova

Shepelyakovskaya

et al. 2021

Sensors

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show abstract

“…Interaction of functionalized QDs and folic acid results in an inhibition of the fluorescence signal. The methodology was used to measure folic acid in fruit juice samples, achieving promising analytical parameters (LOD = 0.1 ng mL −1 ) [ 84 ].…”

Section: Sensing Schemesmentioning

confidence: 99%

Ternary Quantum Dots in Chemical Analysis. Synthesis and Detection Mechanisms

et al. 2021

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Ternary quantum dots (QDs) are novel nanomaterials that can be used in chemical analysis due their unique physicochemical and spectroscopic properties. These properties are size-dependent and can be adjusted in the synthetic protocol modifying the reaction medium, time, source of heat, and the ligand used for stabilization. In the last decade, several spectroscopic methods have been developed for the analysis of organic and inorganic analytes in biological, drug, environmental, and food samples, in which different sensing schemes have been applied using ternary quantum dots. This review addresses the different synthetic approaches of ternary quantum dots, the sensing mechanisms involved in the analyte detection, and the predominant areas in which these nanomaterials are used.

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“…QDs have unique optical properties, such as a wide range of ultraviolet (UV) absorption, narrow fluorescence emission spectrum, high fluorescence intensity, long fluorescence lifetime, and high quantum yield (Kozák et al, 2016; Qie et al, 2019; Tian et al, 2010; Zhang et al, 2018). As an ideal fluorescent marker, QDs have attracted more and more attention and have been used in biological and medical immunoassay (Hou et al, 2020; Novikova, Ponomaryova, & Goryacheva, 2020; Qi, Xu, Liu, & Guo, 2020; Yao et al, 2017; Zhou et al, 2021).…”

Section: Introductionmentioning

confidence: 99%

Quantum dots‐based fluorescence immunoassay for detection of tiamulin in pork

Zhou

Zhang

Qian

et al. 2021

Journal of Food Safety

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Tiamulin (TML) is a kind of diterpenoid veterinary antibiotic. If abused, it will cause residues in edible tissues of animals and endanger human health. Thus, a facile, sensitive, and accurate method is essential for TML detection. In this study, TML complete antigen was synthesized by oximation and active ester method, and monoclonal antibodies with high specificity and sensitivity were prepared. ZnCdSe/ZnS quantum dots (QDs) coupled with goat anti‐mouse IgG were used as a fluorescence detection probe to establish indirect competitive fluorescent immunosorbent assay (icFLISA) for the determination of TML in pork. The 50% inhibitory concentration (IC50) of the icFLISA was 0.069 ng/ml, and the limits of detection (LOD) were 0.309 pg/ml. The recovery of the spiked pork samples for the icFLISA ranged from 85.6 to 96.8%, and the coefficient of variation (CV) was less than 9.4%. The results showed that the icFLISA based on ZnCdSe/ZnS QDs was more sensitive than the traditional indirect competitive enzyme‐linked immunosorbent assay for the detection of TML in edible animal tissues.

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Fluorescent AgInS/ZnS quantum dots microplate and lateral flow immunoassays for folic acid determination in juice samples

Cited by 20 publications

References 39 publications

Antibodies as Biosensors’ Key Components: State-of-the-Art in Russia 2020–2021

Antibodies as Biosensors’ Key Components: State-of-the-Art in Russia 2020–2021

Ternary Quantum Dots in Chemical Analysis. Synthesis and Detection Mechanisms

Quantum dots‐based fluorescence immunoassay for detection of tiamulin in pork

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