Fluorescent carbon nanoparticles: A low-temperature trypsin-assisted preparation and Fe3+ sensing

Feng, Jie; Chen, Yonglei; Han, Yong-Jun; Liu, Juanjuan; Ren, Cuiling; Chen, Xingguo

doi:10.1016/j.aca.2016.04.039

Cited by 93 publications

(45 citation statements)

References 54 publications

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“…It can be seen from Figure B and Supporting Information Table S2 that the fluorescence decay profiles were well fitted by a triexponential function with an obvious shift in average lifetimes, i. e. from 7.94 ns to 5.69 ns before and after addition of Fe 3+ , revealing the excited state interaction between Fe 3+ and GB‐CDs i. e. happening of dynamic quenching. These results strongly confirmed that the fluorescence quenching of as‐synthesized GB‐CDs was due to a combination of IFE and dynamic quenching . This fluorescence quenching was proved by a photograph taken in UV‐light (λ ex = 365 nm) (inset figure A).…”

Section: Resultssupporting

confidence: 76%

A Facile Synthesis of Green‐Blue Carbon Dots from Artocarpus lakoocha Seeds and Their Application for the Detection of Iron (III) in Biological Fluids and Cellular Imaging

et al. 2019

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Herein, a facile, green and eco‐friendly approach has been applied for the synthesis of fluorescent green‐blue carbon dots (GB‐CDs) through the one‐pot hydrothermal treatment of Artocarpus lakoocha seeds for the first time and entirely characterized via a variety of instrumental techniques like fluorescent spectroscopy, Transmission Electron Microscopy (TEM), X‐Ray Photoelectron Spectra (XPS), X‐Ray diffraction (XRD) and Fourier Transform Infra‐red (FTIR) analysis. The as‐prepared GB‐CDs displayed high fluorescent quantum yield (QY) up to 38.5% and high photostability based on which GB‐CDs were successfully applied as a sensitive nanoprobe for the detection of Fe3+ ion. The sensing of Fe3+ shows a linear range from 2 to 6 μM and the limit of detection was found to be 0.62 μM. The sensing of Fe3+ was further investigated in the bona fide sample like river water and human blood serum. In addition, to explore the potential application, MTT assay was carried out on SH‐SY5Y neuroblastoma cells. The results showed negligible cytotoxicity as well as high cell viability, which revealed that GB‐CDs could be utilized as a fluorescent probe in living cells.

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Section: Resultssupporting

confidence: 76%

A Facile Synthesis of Green‐Blue Carbon Dots from Artocarpus lakoocha Seeds and Their Application for the Detection of Iron (III) in Biological Fluids and Cellular Imaging

et al. 2019

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“…The reduction of fluorescence lifetime suggested the occurrence of dynamic quenching [30,41]. The quenching process was further considered to be dynamic because F 0 / F = τ 0 / τ , where τ 0 and τ are the fluorescence lifetimes of Orn-CDs at 404 nm before and after the addition of Fe 3+ , respectively [37,42]. The absorption peak of Orn-CDs/Fe 3+ at 274 nm reduced progressively upon the addition of ascorbic acid (electronic supplementary material, figure S9), indicating the combination of Fe 3+ and Orn-CDs was suppressed and the recovery of Orn-CDs emission by ascorbic acid.…”

Section: Resultsmentioning

confidence: 99%

Nitrogen and chlorine co-doped carbon dots as probe for sensing and imaging in biological samples

Tang

et al. 2019

R. Soc. open sci.

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A facile one-step hydrothermal synthesis approach was proposed to prepare nitrogen and chlorine co-doped carbon dots (CDs) using l-ornithine hydrochloride as the sole precursor. The configuration and component of CDs were characterized by transmission electron microscopy and X-ray photoelectron and Fourier transform infrared spectroscopies. The obtained CDs (Orn-CDs) with a mean diameter of 2.1 nm were well monodispersed in aqueous solutions. The as-prepared CDs exhibited a bright blue fluorescence with a high yield of 60%, good photostability and low cytotoxicity. The emission of Orn-CDs could be selectively and effectively suppressed by Fe3+. Thus, a quantitative assay of Fe3+ was realized by this nanoprobe with a detection limit of 95.6 nmol l−1 in the range of 0.3–50 µmol l−1. Furthermore, ascorbic acid could recover the fluorescence of Orn-CDs suppressed by Fe3+, owing to the transformation of Fe3+ to Fe2+ by ascorbic acid. The limit of detection for ascorbic acid was 137 nmol l−1 in the range of 0.5–10 µmol l−1. In addition, the established method was successfully applied for Fe3+ and ascorbic acid sensing in human serum and urine specimens and for imaging of Fe3+ in living cells. Orn-CD-based sensing platform showed its potential to be used for biomedicine-related study because it is cost-effective, easily scalable and can be used without additional functionalization and sample pre-treatment.

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“…Most of the procedures proposed for metal ions detection are based on fluorescence quenching by metal ions such as the detection of Hg 2+ , [98][99][100][101] Cu 2+ , 102 Fe 3+ , 103 Al 3+ , 104 and Ag + . 103,104,[105][106][107][108] In this detection scheme, metal ions interact with CQDs via surface bonding, which results in the formation of electron-hole recombination via an electron transfer process and changes the fluorescence intensity, used as measurable response signal. 109 CQDs-COOH interact or example with high affinity with Hg 2+ to create new non-radiative hole-pairs, leading to fluorescence quenching.…”

Section: Metal Ion Sensorsmentioning

confidence: 99%

Carbon-based quantum particles: an electroanalytical and biomedical perspective

et al. 2019

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Fluorescent carbon nanoparticles: A low-temperature trypsin-assisted preparation and Fe3+ sensing

Cited by 93 publications

References 54 publications

A Facile Synthesis of Green‐Blue Carbon Dots from Artocarpus lakoocha Seeds and Their Application for the Detection of Iron (III) in Biological Fluids and Cellular Imaging

A Facile Synthesis of Green‐Blue Carbon Dots from Artocarpus lakoocha Seeds and Their Application for the Detection of Iron (III) in Biological Fluids and Cellular Imaging

Nitrogen and chlorine co-doped carbon dots as probe for sensing and imaging in biological samples

Carbon-based quantum particles: an electroanalytical and biomedical perspective

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