Fluorescent-Nanoparticle-Impregnated Nanocomposite Polymeric Gels for Biosensing and Drug Delivery Applications

Abstract

Nanocomposite polymeric gels infused with fluorescent nanoparticles have surfaced as a propitious category of substances for biomedical purposes owing to their exceptional characteristics. The aforementioned materials possess a blend of desirable characteristics, including biocompatibility, biodegradability, drug encapsulation, controlled release capabilities, and optical properties that are conducive to imaging and tracking. This paper presents a comprehensive analysis of the synthesis and characterization of fluorescent-nanoparticle-impregnated nanocomposite polymeric gels, as well as their biomedical applications, such as drug delivery, imaging, and tissue engineering. In this discourse, we deliberate upon the merits and obstacles linked to these substances, encompassing biocompatibility, drug encapsulation, optical characteristics, and scalability. The present study aims to provide an overall evaluation of the potential of fluorescent-nanoparticle-impregnated nanocomposite polymeric gels for biomedical applications. Additionally, emerging trends and future directions for research in this area are highlighted.

New Enhancement Spectrofluorimetric Determination of Anti‐Breast Cancer Drugs Palbociclib by Biogenic‐Synthesized Alumina/NiO Nanocomposite

“…These nanocomposites also have excellent formal and optical properties as well as high sensitivity, which conventional fluorescent probes do not have. [31] In addition, the synthesis of nanocomposite materials is an important step towards various electrical systems, [32] cancer therapy systems [33] and biological probes. [34] In the literature, there is no single stability-indicating fluorescence method for biogenically synthesized nanocomposites.…”

“…They have become a potential alternative to micromaterials. These nanocomposites also have excellent formal and optical properties as well as high sensitivity, which conventional fluorescent probes do not have [31] . In addition, the synthesis of nanocomposite materials is an important step towards various electrical systems, [32] cancer therapy systems [33] and biological probes [34] .…”

Photoluminescent Nanocellulosic Film for Selective Hg2+ Ion Detection

“…CNF typically consist of nanoscale cellulose fibrils characterized by a narrow width (ranging from 5-20 nm) and a length in the micron scale [8]. Recently, CNF-based luminescent nanocomposites have been adopted as substitutes for fossil carbon platforms used for detection and bioimaging [9]. In this regard, luminescence has gained traction for the Polymers 2024, 16, 1583 2 of 11 detection of metal ions, sensing, and bioimaging [10].…”

Nanocomposite Gels Loaded with Flurbiprofen: Characterization and Skin Permeability Assessment in Different Skin Species

“…Emphasis is often placed on nanocomposite gels, which are gel materials with nanoparticles dispersed into their structure. This combination of gel formulations and nanomaterials leads to enhanced formulations with unique physiochemical characteristics [ 21 , 22 ] and synergic effects [ 23 ]. That makes them suitable for diverse biomedical applications such as drug delivery systems, tissue engineering, and wound healing due to their biocompatibility and controlled release capabilities [ 20 , 24 , 25 , 26 ].…”