Fluorescent nanoparticles for chemical and biological sensing

Abstract

Fluorescent nanoparticles (NPs), including quantum dots (QDs), dye-doped NPs, and rare earth-based NPs, etc., have been a major focus of research and development during the past decade. The impetus behind such endeavors can be attributed to their unique chemical and optical properties, such as bright fluorescence, high photostability, large Stocks shift and flexible processability. The introduction of fluorescent NPs into analytical chemistry has opened up new venues for fluorescent analysis. In this review, we focus on the developments and analytical applications of fluorescent NPs in the chemical and biological sensing of pH, ions, organic compounds, small biological molecules, nucleic acids, proteins, virus and bacteria. The review also points out the in vitro and in vivo imaging application of fluorescent NPs at the cell and body levels. Meanwhile, the advantages of NPs brought field of sensing and signal transductions are also discussed. fluorescence, sensing, quantum dots, dye-doped nanoparticles, rare earth-based nanoparticles

Cubic Molecularly Imprinted Polymer Nanoparticles with a Fluorescent Core

“…In order to detect binding, fluorescence is a promising technique, since fluorescent labeling can be a powerful tool for probing the local environment, as well as for biological imaging 5. As a site for placement of a fluorescent label, the NP core is a promising location, since it is isolated from the bulk solution by the surrounding polymer shell.…”

Synthesis of Amphiphilic Hyperbranched AIE‐active Fluorescent Organic Nanoparticles and Their Application in Biological Application

“…[1][2][3][4][5][6][7][8][9] Especially fluorescent organic nanoparticles (FONs) have aroused considerable interest in biological applications because of their biocompatibility, rich chemical modification, biodegradability, and high fluorescence quantum yield (FQY). [10][11][12][13][14][15] FONs, such as fluorescent macromolecules, fluorescent polymeric nanoparticles, and fluorescent supermacromolecular nanoassemblies, have been modified for further conjugation with biomolecules and/or fluorophores.…”

Quantum dot–metallic nanorod sensors via exciton–plasmon interaction

“…Metallic nanoparticles (MNPs) [1,2] and semiconductor quantum dots (SQDs) [3,4] exhibit unique optical, electronic, and magnetic properties which are highly sensitive to the perturbations of their local environments. In conventional nanosensors consisting of MNPs, target binding shifts the wavelength of the local surface plasmon resonance (LSPR) [5,6].…”