Fluorescent tamoxifen derivatives as biophotonic probes for the study of human breast cancer and estrogen-receptor directed photosensitizers

Dı́az, Mario; Hernández, Dácil; Valdés-Baizabal, Catalina; Lobo, Fernando; Marín, Raquel; Canerina-Amaro, Ana; Boto, Alicia; Lahoz, F.

doi:10.1016/j.optmat.2023.113736

Optical Materials

2023

DOI: 10.1016/j.optmat.2023.113736

|View full text |Cite

Fluorescent tamoxifen derivatives as biophotonic probes for the study of human breast cancer and estrogen-receptor directed photosensitizers

Mario Dı́az

Dácil Hernández

Catalina Valdés-Baizabal

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Fluorescence-based techniques for investigating estrogen receptor dynamics

Han,

Choi,

Kim

2024

BMB Rep

View full text Add to dashboard Cite

Understanding estrogen receptor (ER) signaling pathways is crucial for uncovering the mechanisms behind estrogen-related diseases, such as breast cancer, and addressing the effects of environmental estrogenic disruptors. Traditionally, ER signaling involves genomic events, including ligand binding, receptor dimerization, and transcriptional modulation within cellular nuclei. However, recent research have revealed ERs also participate in non-genomic signaling pathways, adding complexity to their functions. Researchers use advanced fluorescence-based techniques, leveraging fluorescent probes (FPb) to study ER dynamics in living cells, such as spatial distribution, expression kinetics, and functional activities. This review systematically examines the application of fluorescent probes in ER signaling research, covering the visualization of ER, ligand-receptor interactions, receptor dimerization, estrogen response elements (EREs)-mediated transcriptional activation, and G-protein-coupled estrogen receptor (GPER) signaling. Our aim is to provide researchers with valuable insights for employing FPb in their explorations of ER signaling.

show abstract

Fluorescence-based techniques for investigating estrogen receptor dynamics

Han,

Choi,

Kim

2024

BMB Rep

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Fluorescent tamoxifen derivatives as biophotonic probes for the study of human breast cancer and estrogen-receptor directed photosensitizers

Cited by 1 publication

References 38 publications

Fluorescence-based techniques for investigating estrogen receptor dynamics

Fluorescence-based techniques for investigating estrogen receptor dynamics

Contact Info

Product

Resources

About