Fluoreto E Inteligência: Avaliação Crítica De Um Estudo De Coorte Prospectivo

Oliveira, Branca Heloísa de; Cruz, Laís Rueda; Normando, David; Cury, Jaime Aparecido

doi:10.29327/244963.6.1-2

Cited by 1 publication

(2 citation statements)

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“…The Green et al. article, which has been previously criticized for failure to provide robust evidence on exposure to fluoride and impaired intelligence, 6 is one of a series of six articles, 5,7‐11 reporting similar analyses conducted by overlapping groups of researchers, using the Canadian Maternal–Infant Research on Environmental Chemicals (MIREC) Study 12 (Table 1). The articles seek to determine whether foetal exposure to fluoride in utero, and through early feeding and infancy, are causally linked to intellectual impairment in childhood.…”

Section: Introductionmentioning

confidence: 99%

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Flawed MIREC fluoride and intelligence quotient publications: A failed attempt to undermine community water fluoridation

Guichon,

Cooper,

Rugg‐Gunn

et al. 2024

Comm Dent Oral Epid

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ObjectiveTo assess the evidence presented in a set of articles that use the Canadian Maternal–Infant Research on Environmental Chemicals (MIREC) study database to claim that community water fluoridation (CWF) is associated with harm to foetal and infant cognitive development.MethodsCritical appraisal of measurements and processes in the MIREC database, and articles derived therefrom. MIREC's cohort is approximately 2000 pregnant women recruited in 10 centres across Canada, 2008–2011, leading to measuring 512 children aged 3–6 years in six cities. Fluoride exposure was measured by city fluoridation status, self‐reports and maternal spot urine samples. Intelligence Quotient (IQ) was measured using the Wechsler Preschool and Primary Scale of Intelligence (WPPSI‐III) by different assessors in each city.ResultsMIREC's fluoride and IQ measurements are invalid and therefore cannot support the claim that CWF is associated with IQ decline in children.ConclusionsThe MIREC fluoride‐IQ articles' results should be considered unacceptable for legal and policy purposes; other water fluoridation studies and systematic reviews show no effect of fluoridation on cognition.

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Section: Introductionmentioning

confidence: 99%

“…has been previously criticized for failure to provide robust evidence on exposure to fluoride and impaired intelligence, 6 is one of a series of six articles, 5,[7][8][9][10][11] reporting similar analyses conducted by overlapping groups of researchers, using the Canadian Maternal-Infant Research on Environmental Chemicals (MIREC) Study 12 (Table 1).…”

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confidence: 99%