Fluoride and Urea Chewing Gums in an Intra-Oral Experimental Caries Model

Abstract

The aim of the present investigation was to evaluate the effect of sugar-free chewing gums containing fluoride (F) and urea in an intra-oral experimental caries model. Placebo chewing gums (without any active ingredient) and no gum served as controls. Fifteen subjects participated in a cross-over, single-blind study. Demineralised enamel and dentine blocks were embedded in circular plastic discs and bonded to the buccal surfaces of the lower canines and first premolars. The discs were removed and analysed using transversal microradiography after each of the six 4-week periods during which the subjects used either test or placebo products or no product. The results revealed that frequent use of sugar-free chewing gum is sufficient to inhibit further demineralisation of previously demineralised enamel and dentine specimens in the oral cavity. Comparing F, urea and placebo gums, the data showed that there was little or no difference between the products, except for an inhibitory effect on the chewing side of the dentition after using F chewing gums.

Effect of a Fluoridated Food Item on Enamel in situ

“…Similar elevated salivary fluoride concentrations could be observed after chewing fluoridated gum [Sjögren et al, 1993[Sjögren et al, , 1997. Because of the increased salivary flow rates in chewing gum studies [Lamb et al, 1993;Sjögren et al, 2002] a mineral gain could also be assessed in the absence of fluorides, which was not the case in the placebo leg of a toothpaste study [Dijkman et al, 1990]. The latter is in accordance with the present findings.…”

The effect of casein and calcium containing paste on plaque pH following a subsequent carbohydrate challenge

“…used in previous studies. 26 The size and amount of the biofilm formed on these surfaces between the lower teeth within 48 h were sufficient to be sure that the probe was placed into plaque. The site between the upper premolars reduced access and increased the possibility of fracture of the probe.…”

Diabetes and Periodontal Infection: Making the Connection

“…[84][85][86] Efferent nerve signals mediated by Volume 23, Number 4, 2005 • CLINICAL DIABETESmucosa will also be dry and sticky or appear erythematous, which could be the result of an overgrowth of Candida albicans. These can be red or white patches or both, often found on the hard or soft palate or dorsal surface of the tongue.…”