Fluoride exposure duringintrauterine and lactation periods promotes changes in the offspring rats' alveolar bone

Ferreira, Maria Karolina Martins; Souza-Monteiro, Deiweson; Bittencourt, Leonardo Oliveira; Matos-Sousa, José Mário; Chemelo, Victória Santos; Santos, Vinicius Ruan Neves dos; Nunes, Paula Beatriz Oliveira; Balbinot, Gabriela de Souza; Prado, Alejandro Ferraz do; Collares, Fabrício Mezzomo; Ager, F.J.; Ortega-Feliú, I.; Respaldiza, M.Á.; Pessanha, Sofia; Lima, Rafael Rodrigues

doi:10.1016/j.chemosphere.2022.136053

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“…The World Health Organization (WHO) recommends a permissible drinking water fluoride level of 1.5 mg/L −1 for maintaining health [ 15 ]. Within this optimal range, fluoride is beneficial for dental health and essential for bone growth and maintenance [ 16 , 17 ]. However, when fluoride concentrations exceed 1.5 mg/L −1 , it can lead to severe health issues, including dental discoloration, skeletal fluorosis, physiological disorders, and kidney malfunctions, among others [ [18] , [19] , [20] ].…”

Section: Introductionmentioning

confidence: 99%