Fluoride gel inhibits caries in children who have low caries-risk but this may not be clinically relevant

Abstract

Fluoride gel inhibits caries in children who have low caries-risk but this may not be clinically relevant Is fluoride gel effective at preventing caries in low caries-risk children?van Rijkom HM, Truin GJ, van't Hof MA. Caries-inhibiting effect of professional fluoride gel application in low-caries children initially aged 4.5-6.5 years. Caries Res 2004; 38:115-123 Design This was a double-blind randomised controlled trial (RCT) conducted over a period of 4 years. Intervention The trial used a semi-annual dental check-up with preventive treatment which consisted of oral hygiene instruction followed by supervised brushing with fluoride toothpaste and either application of a neutral 1% sodium fluoride gel (4500 ppm) or a placebo gel. After the application of the gel participants were advised to refrain from rinsing, eating or drinking for 30 min. (SE, 16%) and 20% (SE, 11%), respectively. This equates to a numberneeded-to-treat of 50 in order to save a subject from 1 D 3 MFS after 4 years. Conclusions In 4.5-to 6.5-year-old children who had low risk of caries, fluoride gel treatment showed a statistically significant cariesinhibiting effect on D 3 MFS, which was considered not clinically relevant, and showed no significant effect on d 3 mfs.

Review on Caries Preventive Effect of Fluoride Toothpaste

“…The study observed that fluoride toothpaste more than 1500ppm have superior caries preventive effect, and has also observed that caries preventive effect is higher in supervised brushing. Another research by Valeria CC Marinho,2004 7 , has concluded that topical fluorides in addition with fluoride toothpaste has modest reduction in dental caries, so both fluoride applications have better enhancement than using only fluoride toothpaste.…”

Optimization of fluoride removal from aqueous solution by Al 2 O 3 nanoparticles

“…Drinking water containing fluoride has both beneficial and detrimental effects on human health [12]. The beneficial effect on the calcification of dental enamel and maintenance of healthy bones considered in the acceptable range of fluoride concentration (1-1.5 mg L -1 ) [13]. On the other hand, consumption of water containing fluoride concentration above the World Health Organization (WHO) guideline value (1.5 mg L -1 ) leads to various health effects viz.…”