Fluoride Ion Release Characteristics of Fluoride-Containing Varnishes—An In Vitro Study

Chhatwani, Sachin; Hoppe, Jennifer; Naumova, Ella A.; Arnold, Wolfgang H.; Möhlhenrich, Stephan Christian; Bizhang, Mozhgan; Danesh, Gholamreza

doi:10.3390/app11041452

Cited by 4 publications

(3 citation statements)

References 33 publications

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“…In an in vitro study by Chhatwani et al ., one of the studied varnishes, Fluor Protector S, showed a peak fluoride release at time 1 (after 20 days of thermal cycling). It can be assumed that Fluor Protector can deliver a high initial level of fluoride release to the surrounding oral cavity environment, but thereafter the fluoride levels fall to a minimum ( 23 ). This is similar to our findings where the FR was statistically different for exposure time according to each varnish.…”

Section: Discussionmentioning

confidence: 99%

Fluoride release from fluoride varnishes exposed to commonly consumed beverages: An in vitro study

Casimiro-Iriarte¹,

Chiok-Ocaña²

2023

J Clin Exp Dent

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Background The aim of this study was to compare the in vitro fluoride release from fluoride varnishes exposed to commonly consumed beverages. Material and Methods One hundred and twenty acrylic blocks were divided randomly into ten experimental groups (n= 12 per group). For the experiment, 24 blocks were prepared for each fluoride varnish (Duraphat®, Duofluorid XII®, Clinpro™, MI Varnish™ and Profluorid®). The blocks were placed into artificial saliva for 30 minutes and in carbonated beverage or fruit juice for up to 24 hours. Artificial saliva and beverages were evaluated to determine the fluoride release using an ion-selective electrode. Data were analyzed using ANOVA F, Friedman and Kruskal Wallis test for bivariate analysis; and three-way ANOVA (fluoride varnish, beverages, exposure time). Results When the fluoride varnishes were compared according to each exposure time, a statistically significant difference was found between all the fluoride varnishes for each evaluation time on carbonated beverage and fruit juice. MI Varnish™ presented the highest fluoride release in carbonated beverage (94.44±5.47ppm) and fruit juice (126.16±8.89ppm) at 8 hours. Duraphat® presented the lowest fluoride release at baseline (0.44±0.08ppm) for carbonated beverage group. A three-way comparison between fluoride release, exposure time and fluoride varnish were statistically significant ( p <0.001). When evaluating the effect of the three independent variables together on fluoride release, it was found that the variables fluoride varnish ( p <0.001) and exposure time ( p <0.001) contributed to the release of fluoride. Conclusions The type of fluoride varnish and the time after the application contribute to the fluoride release model. Key words: Fluorides, topical, sodium fluoride, beverages.

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Section: Discussionmentioning

confidence: 99%

Fluoride release from fluoride varnishes exposed to commonly consumed beverages: An in vitro study

Casimiro-Iriarte¹,

Chiok-Ocaña²

2023

J Clin Exp Dent

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“…The dynamics of fluoride ion release are affected by many factors, e.g., concentration of fluoride ions in the preparation and additional active compounds which interact with fluoride [ 27 , 28 , 29 ].…”

Section: Discussionmentioning

confidence: 99%

Assessment of Microstructure and Release of Fluoride Ions from Selected Fissure Sealants: An In Vitro Study

et al. 2021

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The aim of this study was to compare fluoride release from four selected fissure sealants: fissure sealant manufactured by Arkona, Helioseal F, Helioseal F Plus, and Conseal. Tested parameters included emission of fluoride ions into saline (0.9% NaCl) and deionized water over a period of 2 weeks. Values were recorded after 1, 3, 24, 48, 72, and 96 h, and then after 1 and 2 weeks. All sealants were characterized by a constant fluoride release level. The highest fluoride release level was noted for Conseal (0.0169 ppm/mg), while the lowest was noted for fissure sealant manufactured by Arkona (0.063 ppm/mg). Fissure sealants, which contain fluoride, release it not only during polymerization, but also for several days after application. The use of fissure sealants whose composition includes fluoride is an effective method of preventing tooth decay.

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“…The second-generation varnishes are additionally enriched with calcium and phosphorus compounds in various forms, e.g., as so-called functionalized tricalcium phosphate (β-TCP), amorphous calcium phosphate (ACP), casein phosphopeptide amorphous calcium phosphate nanocomplex (CPP-ACP), calcium sodium phosphosilicate (Novamin) or xylitol-coated calcium phosphate (CXP) [22,23]. According to many researchers [22,[24][25][26][27][28][29][30] these increase the bioavailability of fluoride and the rate of its release as well as improve oral retention and enhance the antibacterial effect. The aim of this study was to evaluate the dynamics of in vitro fluoride ion release from first-and second-generation fluoride varnishes and the impact of the type of varnish, the time from its application and the pH of the environment on this process.…”

Section: Introductionmentioning

confidence: 99%

In Vitro Comparison of the Fluoride Ion Release from the First- and Second-Generation Fluoride Varnishes

2023

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Fluoride varnishes, both the first and the second generations, are effective in inhibiting caries, especially in children and adolescents, by reducing it on average by 43% for permanent teeth and 37% for deciduous teeth. The aim of this study was to evaluate the dynamics of in vitro fluoride ion release from first- (Duraphat) and second-generation (MI Varnish and Embrace Varnish) fluoride varnishes and the impact of the type of varnish, the time from its application and the pH of the environment on this process. Materials and methods: The test material (90 specimens), prepared from extracted human teeth, were divided into nine groups of 10 specimens each. Measured amounts of the examined varnishes were applied onto specimens and the levels of fluoride release were assessed at the baseline and after 1, 2, 24, 48 and 168 h from the application with the use of an ion-specific electrode. The specimens were immersed into artificial saliva with pH adjusted to 4, 5 and 7. The highest cumulative release of fluoride was obtained by MI Varnish (11.52 ppm/mg), regardless of the pH of the environment, whereas the lowest released fluoride concentration was achieved by Embrace Varnish (4.82 ppm/mg). In the acidic environment, the release of fluoride was significantly higher than in the neutral environment for all investigated varnishes, with no change in the overall fluoride release profile and with maximum fluoride release in the first two hours after application. The findings of this study indicate that all examined fluoride varnishes released the maximum amount of fluoride within the first hours after application and that it was related to the acidity of the immersion medium.

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Fluoride Ion Release Characteristics of Fluoride-Containing Varnishes—An In Vitro Study

Cited by 4 publications

References 33 publications

Fluoride release from fluoride varnishes exposed to commonly consumed beverages: An in vitro study

Fluoride release from fluoride varnishes exposed to commonly consumed beverages: An in vitro study

Assessment of Microstructure and Release of Fluoride Ions from Selected Fissure Sealants: An In Vitro Study

In Vitro Comparison of the Fluoride Ion Release from the First- and Second-Generation Fluoride Varnishes

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