Fluoride Releasing Capacity of Newly Developed Atraumatic Restorative Treatment (Art) Material- An in-Vitro Study

Abstract

BACKGROUND Fluoride ion-releasing Atraumatic Restorative Treatment (ART) materials are effective in the prevention of secondary caries. Hence, we have developed new and cost-effective ARTs. The objective of this study is to assess the fluoride releasing capacity of two newly developed Atraumatic Restorative Treatment (ART) materials. MATERIALS AND METHODS Deionized water and freshly prepared artificial saliva were employed to estimate the level of fluoride ion released by two newlydeveloped atraumatic restorative treatment materials (ART-I and ART-II). The release of fluoride anion (F-) released at time-points of 1.0, 24, 168, 360, 720 and 1,440 hrs. were monitored by using an F-Ion-Selective Electrode (ISE) in both media. Statistical analysis was performed using a fixed-effects ANOVA model, together with polynomial and logistic regression approaches. RESULTS Fluoride release in deionized water: The mean Freleased from ART-I material was 9.8 ppm after 1 hr., which increased to a maximum of 40.5 ppm after 168 hrs. However, the Freleased by the ART-II material was 15.7 ppm after 1.0 hr. and 52.7 ppm at the 168 hrs. time-point. Fluoride release in artificial saliva: Freleased from the ART-I material was found to be 6.5 ppm after 1.0 hr. and 48.0 ppm at 168 hrs. For ART-II, the Freleased was 16.12 ppm after 1 hr. a value increasing to a maximum of 35.0 ppm at 168 hrs. CONCLUSION Both the ART-I and II biomaterials were found to release Fthroughout the physiologically-relevant study time-periods incorporated within the experimental design.