Fluorination of some functionalized cycloalkenes through epoxidation and oxirane opening with Deoxofluor or XtalFluor-E

Abstract

A convenient, simple synthetic method is described for the synthesis of some fluorinecontaining, highly functionalized cycloalkane derivatives. The synthetic protocol involves the stereoselective epoxidation of selected substituted cyclohexenes as model compounds, followed by regioselective opening of epoxides under various conditions with fluorinating reagents Deoxofluor and XtalFluor-E.