Fluorine-18 Fluorodeoxyglucose-Positron Emission Tomography: A Highly Accurate Imaging Modality for the Diagnosis of Chronic Musculoskeletal Infections

FDG-PET for diagnosing prosthetic joint infection: systematic review and metaanalysis

“…Reviewing titles and abstracts from PubMed/MEDLINE revealed 20 articles potentially eligible for inclusion [12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31]. Reviewing titles and abstracts from Embase revealed 17 articles potentially eligible for inclusion, which were all already identified by the PubMed/MEDLINE search.…”

“…Thus, 20 studies remained for possible inclusion and were retrieved in full-text version. After reviewing the full article, five articles [18,21,22,25,26] were excluded because the same data were used in another article comprising a larger number of patients, one article was excluded because it did not investigate the diagnostic performance of FDG-PET in detecting prosthetic hip or knee joint infection [14], one article [16] was excluded because the same data were used in another article providing more study details, one article [29] was excluded because less than 15 patients with hip and/or knee prosthesis were investigated, and one article [31] was excluded because it appeared to be an abstract only. Screening references of the remaining articles resulted in one other potentially relevant article [32].…”

FDG-PET Imaging Can Diagnose Periprosthetic Infection of the Hip

“…Another important feature is treatment with antibiotics is not likely to affect the sensitivity of PET in delineating sites of infection because FDG uptake does not rely on leukocyte migration. De Winter et al [5] reported that FDG-PET is considerably more accurate than the combination of bone scan and white blood cell scan for diagnosing chronic infections in the central skeleton (p \ 0.05) with a sensitivity, specificity, and accuracy of 100%, 90%, and 94%, respectively.…”

Patient and Personnel Radiation Exposure in Sentinel Lymph Node Practice

“…Bu konu ile ilgili ilk çalışmalar umut verici olmuş, tüm vücut ve organ dozimetrileri In-111 lökosit sonuçları ile karşılaştırıldığında benzer bulunmuştur (43,44). Fizyolojik kemik iliği tutulumunun olmaması, ayrıca PET tekniğinin yüksek uzaysal rezolüsyon ile yüksek kalitede görüntüleri ve testin oldukça kısa sürede (2-3 saat) tamamlanması nedeni ile diğer konvansiyonel radyonüklidik görüntülemelere göre avantaj sağlamaktadır (45). Ancak, bu yöntemin de bazı kısıtlılıkları vardır.…”