Fluoroscopy-Guided Salvage Photodynamic Therapy Combined with Nanoparticle Albumin-Bound Paclitaxel for Locally Advanced Esophageal Cancer After Chemoradiotherapy

Zhao, Wenzhi; Zhao, Jing; Kang, Lin; Li, Chen; Xu, Zhen-Ning; Li, Jing; Zhang, Ming

doi:10.1089/cbr.2020.4595

Cited by 8 publications

(8 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Nakamura et al reported an elderly patient with an advanced GC, to be successfully treated with repeated PDT using talaporfin sodium (19). Compared with PDT alone, some combination therapies can significantly reduce the postoperative recurrence rate of PDT (5). With regard to esophageal cancer, the efficacy and one-year survival rate of PDT combined with chemotherapy were significantly higher than those of chemotherapy as a single treatment regimen (20).…”

Section: Discussionmentioning

confidence: 99%

“…Nevertheless, the operation of simultaneous or sequential bimetallic stents placement is difficult due to limited interspace, and uncovered stents cannot prevent tumor progression, and tumor oppression reemerges obstructions. On the contrary, photodynamic therapy (PDT) is a noninvasive interventional treatment applied in the management of gastrointestinal tumors (5). A patient with GC and pyloric duodenal and biliary obstruction complications was admitted to our health center.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Photodynamic therapy combined with bimetallic stent in the treatment of gastric cancer with malignant duodenobiliary obstruction: a case report and literature review

Wang¹,

Wang²,

Zhang³

et al. 2022

Transl Cancer Res TCR

View full text Add to dashboard Cite

Background: Patients with advanced gastric cancer (GC) often and can develop simultaneous or sequential duodenal and biliary obstructions resulting in reduced quality of life and significantly a reduction in the survival time. However, palliative management, insertion of biliary and duodenal metallic stents can relief these obstructions and has become a feasible and safe therapeutic strategic option. However, the operation of bimetallic stents placement is much more difficult and challenging, for instance, cannot prevent tumor progression and reemerge obstructions.Case Description: This report describes and elucidates a patient with GC who has complicated duodenal and biliary obstructions. In this case, the patient was already at an advanced stage when diagnosed, and the patient had a past medical history of cardiac and pulmonary disorders, with the poor general condition and no chance of undergoing any form of laparoscopic surgery. Furthermore, this patient developed severe symptoms of duodenal and biliary obstructions which have resulted in having nutritional disorders and liver dysfunctions post chemotherapeutic treatment regimens. In order to get rid of those obstructions, endoscopic photodynamic therapy (PDT) combined with duodenal metal stent and biliary metal stent was utilized for palliative treatment. In addition, such combined strategies can provide a longer survival time (11 vs. 7.6 months reported before) and improve the quality of life for patients with GC at an advanced stage.Conclusions: PDT combined with bimetallic stents is a safe and excellent therapeutic strategy for advanced GC which has complicated duodenal and biliary obstructions.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Photodynamic therapy combined with bimetallic stent in the treatment of gastric cancer with malignant duodenobiliary obstruction: a case report and literature review

Wang¹,

Wang²,

Zhang³

et al. 2022

Transl Cancer Res TCR

View full text Add to dashboard Cite

show abstract

“…[288][289][290][291] For PTT, by using selective photothermal absorbers, difficult-to-treat tumors can be targeted with minimal aggressiveness. [292][293][294][295] PTT has the advantages of small adverse effects, high specificity, and reproducible treatment, which shows significant advantages compared with the traditional tumor treatment modalities. However, heat shock and insufficient light penetration have also become shortcomings in therapeutic advantages.…”

Section: Other Treatment Methodsmentioning

confidence: 99%

Catalytic nanotechnology of X-ray photodynamics for cancer treatments

Zhang

Guo

et al. 2023

Biomater. Sci.

View full text Add to dashboard Cite

show abstract

“…The potential role of PDT in functionalized nanomedicine is often highlighted ( 115 , 116 ). Fluoroscopy-guided PDT by using nanoparticle albumin-bound paclitaxel for esophageal cancer after chemoradiotherapy is known and well-described ( 117 ).…”

Section: Development Opportunitiesmentioning

confidence: 99%

Advancements in photodynamic therapy of esophageal cancer

et al. 2022

View full text Add to dashboard Cite

The poor prognosis of patients with esophageal cancer leads to the constant search for new ways of treatment of this disease. One of the methods used in high-grade dysplasia, superficial invasive carcinoma, and sometimes palliative care is photodynamic therapy (PDT). This method has come a long way from the first experimental studies to registration in the treatment of esophageal cancer and is constantly being improved and refined. This review describes esophageal cancer, current treatment methods, the introduction to PDT, the photosensitizers (PSs) used in esophageal carcinoma PDT, PDT in squamous cell carcinoma (SCC) of the esophagus, and PDT in invasive adenocarcinoma of the esophagus. For this review, research and review articles from PubMed and Web of Science databases were used. The keywords used were “photodynamic therapy in esophageal cancer” in the years 2000–2020. The total number of papers returned was 1,000. After the review was divided into topic blocks and the searched publications were analyzed, 117 articles were selected.

show abstract

Fluoroscopy-Guided Salvage Photodynamic Therapy Combined with Nanoparticle Albumin-Bound Paclitaxel for Locally Advanced Esophageal Cancer After Chemoradiotherapy

Cited by 8 publications

References 27 publications

Photodynamic therapy combined with bimetallic stent in the treatment of gastric cancer with malignant duodenobiliary obstruction: a case report and literature review

Photodynamic therapy combined with bimetallic stent in the treatment of gastric cancer with malignant duodenobiliary obstruction: a case report and literature review

Catalytic nanotechnology of X-ray photodynamics for cancer treatments

Advancements in photodynamic therapy of esophageal cancer

Contact Info

Product

Resources

About