2016
DOI: 10.5935/0100-4042.20160098
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Fluorous Supported Synthesis of Pyrazolone Derivatives From Allylic Alcohols Using a Palladium-Catalyzed Strategy

Abstract: publicado na web em 06/06/2016Ten substituted pyrazolone derivatives were easily synthesized from perfluorinated allylic alcohols, via a straightforward two steps reaction involving a Heck-coupling/isomerization reaction and subsequent condensation of hydrazines. This fluorous supported methodology, that combines a cyclo-release approach and F-SPE purification allows for the obtaining of the final products with a good purity.

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