The fundamental approach to improve pilots’ situation awareness (SA) would be to reorganize and restructure the presentation of information to fit pilot's cognitive model on the flight deck. This would facilitate pilots’ perception, understanding, and projection, hence making it easier to find the relevant targets. Sixty pilots (30 B‐737 pilots and 30 B‐777 pilots) participated in this study to investigate pilots’ SA while interacting with digital displays and moving pointed needle displays on cabin pressurization system. The results have shown significant differences on pilots’ perception, understanding, and overall SA between digital display and pointed display on the flight deck. Pilots significantly preferred the digital design cabin pressurization system, which is consistent with the proximity compatibility principle, and the position of the display on the center instrument panel is easily accessible to both pilots and does not require large head movements. There are some recommendations on the cabin pressurization design including the size of outflow valve position indicator, which should be significantly increased to provided saliency of information; color coding should be used on cabin altitude and differential pressure indicator to mark critical cabin altitude; and standard operating procedures shall include cabin altitude and differential pressure reading by pilot monitoring. The final and completed solution to the issues on the cabin pressurization system is to redesign the scattered pointed displays as integrated digital displays to fit the human‐centered principle.