FMRI and EEG Reactions to Hand Motor Tasks in Patients with Mild Traumatic Brain Injury: Left-Hemispheric Sensitivity to Trauma

Жаворонкова, Л. А.; Moraresku, S. I.; Boldyreva, G. N.; Sharova, E. V.; Kuptsova, S. V.; Смирнов, А. С.; Masherov, E. L.; Maksakova, O. A.; Pronin, Igor

doi:10.4236/jbbs.2019.96020

Cited by 10 publications

(5 citation statements)

References 34 publications

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“…Higher motor activation in the right hemisphere than in the left hemisphere (C4 vs. C3 ROI electrodes) indicated higher arousal associated with the involvement of the left hand. Since our participants were right-handed, higher amplitudes may indicate the involvement of additional resources to manage the movements of the non-leading hand under challenging tasks (Zhavoronkova et al, 2019;Serrien & Spape, 2009).…”

Section: Discussionmentioning

confidence: 99%

“…Accounting for brain functional asymmetry, we have expected to identify some differences in the functioning of the right and left hemispheres potentially associated with the leading and non-leading hand (Serrien & Spape, 2009;Zhavoronkova et al, 2019). Aiming to better interpret the results of our exploratory study, we have added control over participants' handedness by including right-handed participants only.…”

Section: Introductionmentioning

confidence: 99%

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Human, Technologies and Quality of Education, 2023

2023

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The aim of the study was to explore social measurements and COVID-19 -related behavioral choices from a network structure perspective. We tested network models by comparing network structures in 46 countries by cultural dimensions (Hofstede et al., 2010). The pre-registered hypothesis was that the network structure of variables predicting COVID-19-related behavioral choices will be robust across countries, regardless of the mean differences of these variables between countries characterized by high vs low culture dimension indices. Behavioural choices toward COVID-19 situation were: physical hygiene, policy support, and physical contact. In network analysis we used several social/psychological constructs: social belonging, trait optimism, collective narcissism, moral identity, self-esteem, national identification, trait self-control, morality as cooperation, conspiracy beliefs, political ideology, and narcissism. We analysed twelve conditions based on dichotomized culture dimensions (high vs. low Power distance, Individualism, Masculinity, Uncertainty avoidance, Long-term orientation, and Indulgence) across demographics (e.g., age, gender). We conducted network structure analysis using high-dimensional undirected graph estimation with glasso procedure splitting the data by culture dimensions in total with N = 40 795 individuals. The study findings indicated that the network models were fairly consistent across cultures with different scores on each of Hofstede's six cultural dimensions. This similarity reflects the previous studies in terms of the stability of associations between variables regardless of sex, age, and political beliefs.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Human, Technologies and Quality of Education, 2023

2023

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Exploration of EEG Markers of Sensorimotor Functioning During Incorrect versus Correct Decisions

Kolesovs,

Evelis,

Ozolina-Molla

et al. 2023

Human, Technologies and Quality of Education, 2023

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Open-skill sports are demanding for athletes’ decision-making. Incorrect decisions can have substantial consequences. Complex programs for elite athletes include improvement of their neurocognitive functioning. Simultaneously, making errors remains underrepresented in broader sports science. The present study explored EEG markers of sensorimotor reactions under incorrect versus correct responses to visual stimuli. Seven male participants (24.2±2.5 years) completed the Choice Response Time task (CRT) with simultaneous EEG registration. Two color stimuli (red and green) and a discriminative stimulus (black) were presented on an LCD screen, using PSYCHOTOOLBOX coded CRT task. Stimulus and response events were synchronized with EEG amplifier NVX-136, and 32 channels of EEG were recorded. Data were preprocessed in EEGLAB, and event-related potential (ERP) calculations were performed in ERPLAB. ERP was analyzed for correct and incorrect color choices and reactions to the discriminative stimulus. The electrodes represented the visual (O1, Oz, O2), frontal (F3, Fz, F4), and sensorimotor (C3, Cz, C4) cortex. Behavior data revealed a shorter reaction time during the incorrect decision (4.6% of cases) than during the correct one, 398.1±55 ms vs. 456.8±96 ms. In the N2 peak area, the incorrect color stage differed significantly from the two correct stages (e.g., the amplitude of -1.624 mkV at a latency of 264 ms for the correct color stage and -1.779 mkV at a latency of 254 ms for the correct discriminating stage vs. -3.716 mkV at a latency of 300 ms for the incorrect color stage for channel F3, peak N2). Correct decision stages had similar ERP wave peak patterns. Incorrect decisions deviate from functioning during correct ones. Differences in the N2 peak area represented conflict in decision-making during incorrect decisions. Simultaneously, the shorter latency of a motor reaction requires investigating the role of decision-making conflicts in impulse control and behavioral consequences.

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“…Полученные нами данные дополняют литературные, в которых показано, что основной корковый ответ на выполнение активной и пассивной пробы обнаруживается в сенсомоторной области контралатерального по отношению к работающей руке полушария, дополнительной моторной коре, мозжечке [21][22][23]. Важной особенностью двигательных фМРТ-ответов у пациентов с тяжелой ЧМТ, отмечаемой во многих публика-циях, является нарастание диффузности гемодинамических изменений с активацией нехарактерных для здорового человека отделов мозга [24][25][26][27], а данные коннективности показывают, что это может быть следствием активизации подкорковых структур.…”

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Methodical Approach to fMRI Assessment of Motor Connectome in Patients After Severe Traumatic Brain Injury

Stern

Sharova

Жаворонкова

et al. 2023

Obŝaâ reanimatologiâ

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The aim of the study. To identify alterations of motor connectome in patients with varying degrees of hemi-paresis after severe traumatic brain injury (TBI) versus healthy volunteers.Material and methods. The study included 29 patients with TBI aged 18 to 35 years and 23 healthy volunteers aged 20 to 32 years. Participants underwent a comprehensive clinical and neuroimaging study. Motor impairment was evaluated via muscle strength assessment using a five-score scale. The fMRI data were processed using a dedicated CONN software package. Anatomical 3-D connection masks of the whole brain motor functional system in the predetermined regions of interest (ROIs) were used for the assessment. Then the group indicators of functional connectivity (statistical significance of the connection) were computed.Results. It was established that the structure of connections in healthy individuals performing active movement with the right (leading) hand is determined by formation of focus in the cortical and subcortical ROIs in the contralateral hemisphere. With passive movement of the right hand the pale ball becomes functionally active in addition to the activated areas. The striopallidar system structures became active on both sides, and connectivity with the additional motor cortex and the motor cortex of the ipsilateral hemisphere emerged as the paresis increased during active movement. The focus of motor activity during passive movement was determined in the motor cortex and putamen, which makes it possible to use a passive test in patients with gross motor disorders or unconsciousness for a full assessment of the entire structural and functional brain connectome.Conclusion. As hemiparesis increased in patients after severe traumatic brain injury, a decrease in the total number of connection appeared; simultaneous engagement of ancient primordial structures, such as bilateral activation of pale globes, demonstrated neuroplasticity.

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FMRI and EEG Reactions to Hand Motor Tasks in Patients with Mild Traumatic Brain Injury: Left-Hemispheric Sensitivity to Trauma

Cited by 10 publications

References 34 publications

Human, Technologies and Quality of Education, 2023

Human, Technologies and Quality of Education, 2023

Exploration of EEG Markers of Sensorimotor Functioning During Incorrect versus Correct Decisions

Methodical Approach to fMRI Assessment of Motor Connectome in Patients After Severe Traumatic Brain Injury

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