Focal Epithelial Hyperplasia Caused by Human Papillomavirus 13

Saunders, Natasha; Scolnik, Dennis; Rebbapragada, Anu; Koelink, Eric; Craw, Lindsey; Roth, Sherryn; Aronson, Leya; Perusini, Stephen; Silverman, Michael

doi:10.1097/inf.0b013e3181cf854c

Cited by 12 publications

(3 citation statements)

References 8 publications

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“…Referring to age and gender Saunders et al and Ledesma et al, reported that FEH mainly affects the pediatric population and the condition is more common among women (19,20) , coinciding with the current report of four cases, which mostly affected women with three cases and the age range was between 7 and 14.…”

Section: Discussionsupporting

confidence: 83%

Treatment of focal epithelial hyperplasia with trichloroacetic acid

Ricardo¹,

Lorduy

Caballero³

2012

Rev. Clin. Periodoncia Implantol. Rehabil. Oral

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Focal epithelial hyperplasia is a benign disease which has a chronic course that manifests as characteristic multiple small papules or nodules. They are predominantly found in the oral mucosa, gingiva and tongue. The surface of the lesions is smooth and it varies in size. It is an asymptomatic disease caused by human papillomavirus, affecting mainly children and adolescents. In this report, we describe four cases referred to the Stomatology and Oral Surgery Department of the Faculty of Dentistry, Cartagena University with a diagnosis of focal epithelial hyperplasia. Clinical features and histopathological characteristics of the patients were recorded. We also describe the properties and advantages of trichloroacetic acid as a therapeutic method.

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Section: Discussionsupporting

confidence: 83%

Treatment of focal epithelial hyperplasia with trichloroacetic acid

Ricardo¹,

Lorduy

Caballero³

2012

Rev. Clin. Periodoncia Implantol. Rehabil. Oral

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“…It manifests in the oral mucosa and is caused by human papilloma virus. It is related to subtypes 13 and 32; 1,2 it is common in North American native subjects. In Colombia it is mostly found in the Antioquìa and Chocó districts.…”

Section: Introductionmentioning

confidence: 99%

Effectiveness of trichoroloacetic acid in treatment of focal epithelial hiperplasia lesions

Ricardo¹,

Lorduy²,

Caballero³

2016

Revista Odontológica Mexicana

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Objective:The aim of the present study was to assess effectiveness of trichloroacetic acid therapy in the treatment of oral lesions produced in focal epithelial hyperplasia cases. Material and methods: In the present study 11 patients were included. Patients exhibited clinical and histopathological characteristics of focal hyperplasia and were willing to participate in the study. Convenience sampling was executed in patients attending clinical consultation at the Dental Clinic of the Rafael Nuñez University Corporation and the University of Cartagena. Patients underwent excision biopsy in one of the lesions so as to establish anatomical-pathological diagnosis. Subsequently, 80% trichloroacetic acid was applied every two weeks on the lesions, until lesions disappeared. Results: Out of 11 pediatric patients 63.64% were female, average age nine years. Locations of greater involvement in the mouth were upper and lower labial mucosa (representing 100%). Anatomical-pathological study revealed in all cases presence of epithelial acanthosis, papillomatosis and koilocytiosis. The greatest number of acid applications was three and four episodes with 27%, average time for lesion disappearance was 61.3 days. No relapse was observed in 100% of cases. Conclusion: Trichloroacetic acid application in focal epithelial hyperplasia cases is an effective technique which achieves rapid, atraumatic stress-free lesion resolution which did not generate fear in involved patients.

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“…Multifocal epithelial hyperplasia (MEH) is an uncommon disease characterized by the proliferation on the oral mucosa of multiple papulonodular lesions, which are smooth, soft on palpation and generally asymptomatic (1)(2)(3)(4)(5). It has mainly been observed among isolated groups of native Indians in North, Central and South America and in other very small population groups in Europe and Africa (6)(7)(8)(9)(10)(11)(12)(13).…”

Section: Introductionmentioning

confidence: 99%

Multifocal epithelial hyperplasia: A potentially precancerous disease? (Review)

Bascones-Martínez¹,

Cok²,

Bascones-Ilundáin³

et al. 2011

Oncology Letters

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Abstract. Multifocal epithelial hyperplasia (MEH), also known as Heck's disease, manifests as a papulonodular lesion in the oral mucosa and has been associated with the human papillomavirus, a virus related to various precancerous diseases in the oral cavity. It has a predisposition for the female gender and for children. Although the majority of reported cases have been among American Indians and Eskimos, it has been described in multiple ethnic groups in various geographical locations. The objective of this review was to report on the clinical characteristics and epidemiology of MEH and its possible correlation with oral cancer. It is based on a search of articles in international journals published prior to April 2011, using the PubMed database and selecting articles related to the epidemiology and clinical characteristics of MEH. The review revealed a higher number of cases in individuals of American Indian origin and a predilection of the disease for the female gender and for patients between the 1st and 2nd decades of life. The most frequent lesion site was the lower lip. The disease has been associated with socio-economic and genetic factors, among others. No cases of malignant transformation have been reported.

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Focal Epithelial Hyperplasia Caused by Human Papillomavirus 13

Cited by 12 publications

References 8 publications

Treatment of focal epithelial hyperplasia with trichloroacetic acid

Treatment of focal epithelial hyperplasia with trichloroacetic acid

Effectiveness of trichoroloacetic acid in treatment of focal epithelial hiperplasia lesions

Multifocal epithelial hyperplasia: A potentially precancerous disease? (Review)

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