A 69-year-old woman diagnosed with papillary thyroid carcinoma was treated with total thyroidectomy and radioiodine ablation. At follow-up a whole body I-131 scan after injection of rhTSH was performed. This scan shows unexpected uptake in the superior mediastinum, initially misinterpreted as metastases (Tg level: 6.8 ng/mL). CT and digital subtraction angiography (DSA) confirmed that this finding was due to an aortic aneurysm. This vascular malformation was embolized and endoprosthesis was performed using a Seldinger's technique.