Focal Residual Contrast Media in the Kidney 24 Hours after Angiography

Yamazaki, Hideya; Oi, Hiromichi; Matsushita, Masaki; Koizumi, Masahiko; Kagawa, Kiyosumi; Tanaka, Eiichi; Murayama, Shigeyuki; Nose, Takayuki; Teshima, Teruki; Inoue, Toshinori; Inoue, T

doi:10.1177/02841851960371p173

Acta Radiol

1996

DOI: 10.1177/02841851960371p173

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Focal Residual Contrast Media in the Kidney 24 Hours after Angiography

Hideya Yamazaki

Hiromichi Oi

Masaki Matsushita

et al.

Abstract: Delayed CT showed a higher incidence of injury to the renal parenchyma than previously detected by conventional radiography.

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Persistent CT nephrograms following cardiac catheterisation and intervention: initial observations

Katzberg¹,

Monsky²,

Prionas³

et al. 2011

Insights Imaging

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ObjectivesTo describe persistent nephrographic patterns detected by unenhanced renal CT at 24 h after cardiac catheterisation and intervention.MethodsThis prospective study was Health Insurance Portability and Accountability Act-compliant and institutional review board approved. Twenty-nine patients (20 men, nine women; average age 63.27 and range 41–85 years) agreed to undergo unenhanced dual-energy computed tomography (CT) limited to their kidneys at 24 h after cardiac catheterisation. CT attenuation values (Hounsfield units) were made from the cortical and medullary regions and single kidney total parenchymal iodine values (milligrams) were measured. Spearman’s rank correlation coefficient and a two-sided Fisher’s exact test were used in the statistics.ResultsFocal nephrograms were observed in at least one kidney (range, one to five regions per kidney) in 10/29 (34%) of patients and bilateral global nephrograms in 13/29 (45%) of patients. Focal nephrograms correlated with cardiac catheterisation fluoroscopic time (r = 0.48; P = 0.0087). For global nephrograms, the total iodine content of right and left kidneys correlated with fluoroscopic time (r = 0.79 and 0.76; P < 0.0001, respectively) and the amount of contrast material (CM) used (r = 0.77 and r = 0.74; P < 0.0001, respectively).ConclusionPersistent focal and global nephrograms occur commonly as assessed by non-contrast CT at 24 h post cardiac catheterisation and our observations suggest they could be related to procedural factors.Electronic supplementary materialThe online version of this article (doi:10.1007/s13244-011-0131-2) contains supplementary material, which is available to authorized users.

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Persistent CT nephrograms following cardiac catheterisation and intervention: initial observations

Katzberg¹,

Monsky²,

Prionas³

et al. 2011

Insights Imaging

View full text Add to dashboard Cite

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Retention of Iodine and Expression of Biomarkers for Renal Damage in the Kidney After Application of Iodinated Contrast Media in Rats

Jošt¹,

Pietsch²,

Sommer³

et al. 2009

Investigative Radiology

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A prolonged retention of contrast media in the kidney was observed after administration of dimeric CM (Iodixanol 320). One possible explanation for this effect could be the high viscosity of the dimeric CM (Iodixanol 320) and the lack of dilution by osmotic diuresis. This prolonged exposure is possibly associated with higher renal toxicity as indicated by the elevated expression of biomarkers for hypoxia and renal injury.

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Focal Residual Contrast Media in the Kidney 24 Hours after Angiography

Abstract: Delayed CT showed a higher incidence of injury to the renal parenchyma than previously detected by conventional radiography.

Cited by 2 publications

References 22 publications

Persistent CT nephrograms following cardiac catheterisation and intervention: initial observations

Persistent CT nephrograms following cardiac catheterisation and intervention: initial observations

Retention of Iodine and Expression of Biomarkers for Renal Damage in the Kidney After Application of Iodinated Contrast Media in Rats

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