2021
DOI: 10.1101/2021.03.18.435995
|View full text |Cite
Preprint
|
Sign up to set email alerts
|

Focal seizures are organized by feedback between neural activity and ion concentration changes

Abstract: Human and animal EEG data demonstrate that focal seizures start with low-voltage fast activity, evolve into rhythmic burst discharges and are followed by a period of suppressed background activity. This suggests that processes with dynamics in the range of tens of seconds govern focal seizure evolution. We investigate the processes associated with seizure dynamics by complementing the Hodgkin-Huxley mathematical model with the physical laws that dictate ion movement and maintain ionic gradients. We show that t… Show more

Help me understand this report
View published versions

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
0
0

Publication Types

Select...

Relationship

0
0

Authors

Journals

citations
Cited by 0 publications
references
References 132 publications
(229 reference statements)
0
0
0
Order By: Relevance

No citations

Set email alert for when this publication receives citations?