Foeniculum vulgare therapy in irritable bowel syndrome

Amjad, Hassan; Jafary, H.A.

doi:10.1111/j.1572-0241.2000.02633.x

Cited by 10 publications

(7 citation statements)

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“…Anethole, the major component of fennel oil seeds, is chemically similar to the neurotransmitter dopamine, and has a relaxant effect on intestinal smooth muscle, isolated rat uterus [22], and guinea pig trachea rings [23]. In a pilot study on IBS patients, the fennel reduced abdominal pain, a mechanism likely mediated by the anethole-dependent relaxation of intestinal smooth muscle [24].…”

Section: Introductionmentioning

confidence: 99%

Curcumin and Fennel Essential Oil Improve Symptoms and Quality of Life in Patients with Irritable Bowel Syndrome

Portincasa

Bonfrate

Scribano

et al. 2016

JGLD

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Section: Introductionmentioning

confidence: 99%

Curcumin and Fennel Essential Oil Improve Symptoms and Quality of Life in Patients with Irritable Bowel Syndrome

Portincasa

Bonfrate

Scribano

et al. 2016

JGLD

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“…This therapeutic effect has been confirmed by a recent systematic review of interventions in breast-fed infants [ 43 ]. The efficacy of fennel in reducing abdominal pain has also been suggested by a preliminary report involving adult IBS patients [ 44 ]. Taken together, these previous findings should justify the combination of the two herbal products as a possible and useful therapeutic tool in IBS patients.…”

Section: Discussionmentioning

confidence: 99%

“…Since the present study was not designed to observe patients further after treatment withdrawal, studies should also be targeted to explore symptom recurrence after the suspension of therapy and, in view of previous results of beneficial effects in IBS patients of curcumin [ 37 ] and fennel seed oil [ 44 ] given separately, to assess if the association of these components is able to give better results than either component alone.…”

Section: Discussionmentioning

confidence: 99%

Efficacy of bio-optimized extracts of turmeric and essential fennel oil on the quality of life in patients with irritable bowel syndrome

Ciaula¹

2018

aog

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BackgroundThe use of herbal products to treat irritable bowel syndrome (IBS), a disease that frequently affects the quality of life (QoL), is still under evaluation. This open pilot study assessed the efficacy of bio-optimized extracts of turmeric and essential fennel oil (Enterofytol®) in IBS patients.MethodsA total of 211 patients (14% diarrhea-predominant, IBS-D; 24% constipation-predominant, IBS-C; 62% mixed, IBS-M) were enrolled by general practitioners and completed questionnaires measuring symptom severity and QoL before and after Enterofytol®, two capsules b.i.d. for one month, followed by two capsules q.d. for another month.ResultsIBS severity index and QoL were inversely related. A significant reduction in the severity index and an improvement in QoL were evident following treatment in all IBS subgroups. IBS-D patients showed the worst clinical picture at entry, with the highest IBS severity index and the lowest QoL score, compared with IBS-C and IBS-M subtypes. IBS-D patients, however, also showed the most pronounced response to therapy, considering both scores. The improvement in the IBS severity index was independent of age and sex.ConclusionsResults from this “real-life” study show that the combination of turmeric and essential fennel oil over two months improves both symptoms and QoL in IBS patients, irrespectively of age, sex, initial severity of symptoms and IBS-subtypes, suggesting a potential role for the natural treatment of IBS.

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“…In a pilot study on IBS patients, the fennel reduced crampiform abdominal pain, a mechanism likely mediated by the anethole-dependent relaxation of intestinal smooth muscle [122]. The combination of curcumin-fennel essential oil has been recently used by our group and has improved symptoms and quality of life in IBS patients [123].…”

Section: Common Dietary Targets In Treating Ibsmentioning

confidence: 99%

Irritable bowel syndrome and diet

Portincasa

Bonfrate

Bari

et al. 2017

Gastroenterology Report

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Irritable bowel syndrome (IBS) is a chronic functional disorder of the gastrointestinal tract and is one of the most commonly diagnosed gastrointestinal diseases. The impact of IBS on the general population is large due to its high prevalence, suboptimal medical treatments and significant economic burden. The pathophysiology of IBS is complex and treatments are often symptom-specific. The most common therapeutic approaches for IBS include education and reassurance, lifestyles (especially nutrition-based interventions), peripherally acting medications (which typically target motility), centrally acting medications (which target visceral hypersensitivity and pain) and psychological interventions (which aim to reduce the effects of stress or symptom-specific anxiety). A beneficial dietary approach might include the following measures: a diet low in fermentable oligo-,di- and monosaccharides and polyols (FODMAPs), limitation or exclusion of gas-producing foods and/or lactose and gluten and fiber supplementation in selected cases. New therapeutic agents, namely nutraceutics, are also an interesting option in the management of IBS patients. This paper will focus on available dietary interventions for IBS and will review the evidence for nutrition-based therapies.

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Foeniculum vulgare therapy in irritable bowel syndrome

Cited by 10 publications

References 0 publications

Curcumin and Fennel Essential Oil Improve Symptoms and Quality of Life in Patients with Irritable Bowel Syndrome

Curcumin and Fennel Essential Oil Improve Symptoms and Quality of Life in Patients with Irritable Bowel Syndrome

Efficacy of bio-optimized extracts of turmeric and essential fennel oil on the quality of life in patients with irritable bowel syndrome

Irritable bowel syndrome and diet

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