Application of high-performance computer systems and microcontrollers in food quality monitoring pays extra attention to their improvements in accuracy, efficiency, and real-time analysis. Advanced microcontrollers allow the accomplishment of more precise monitoring of critical parameters such as temperature, humidity, and gas composition in order to ensure food safety and quality from supply chain outlets. Innovations in sensor technology, data processing, and wireless communication gave birth to smart systems for detecting contamination, spoilage, or adulteration. These systems feed real-time data that enables instantaneous decisions and reduces food waste. Microcontroller-based solutions allow for IoT connectivity and machine learning algorithms with a better possibility of predictive analytics and automation in the management of food quality. The chapter is focused on the key technologies, applications, and challenges, giving insight into the future regarding food quality monitoring in this very connected world, particularly about food industries.