Follicular cystitis in a dog

Abstract

A four-year-old female Cavalier King Charles Spaniel with a history of recurrent lower urinary tract disease refractory to treatment was referred to our hospital. Clinical examination was unremarkable apart from thickening of the dorsal vulva. Abdominal ultrasound was compatible with possible areas of mild thickening of the bladder wall. Lower genitourinary-contrast radiographic studies showed multiple small lesions in the bladder wall. Surgical biopsy of the bladder was compatible with follicular cystitis and excised uterine tissue was consistent with cervicitis. Clinical signs resolved after treatment with a combination of antibiosis, NSAIDs, pentosan polysulfate and amitriptyline. Follow-up 30 months after surgery confirmed that the dog was free of clinical signs. Follicular cystitis has not been previously reported in dogs but should be considered as a differential for patients with refractory long-standing lower urinary tract disease.

Follicular cystitis in a dog: First case report described in Brazil

“…Ediz et al (2017) states that the disease should be particularly considered in women over 50 years old with a recurrent history of urinary infections and hematuria. In veterinary medicine, however, there is only one report of the disease in a female dog, being the present study the second report in the species, and, unlike humans, both are young adults (Sul et al, 2014).…”

“…Follicular cystitis is a rare inflammatory disease that leads to non-specific symptoms in the urinary tract (Somvanshi et al, 2012;Sul et al, 2014;Ediz et al, 2017). In humans, the disease mostly affects adult females (Marsh et al, 1974;Blanco et al, 2007).…”

“…In these cases, more details about the type and cause of inflammation are obtained through the proteinogram. It is noteworthy that a large part of the data is extrapolated from the medical literature due to the reduced number of specific subsidies reported in patients in veterinary medicine (Sul et al, 2014).…”

“…Follicular cystitis has also been reported in buffaloes in India and in cattle and buffaloes in Turkey (Somvanshi et al, 2012). A report in dog has been described in the United Kingdom (Sul et. al., 2014).…”

Ureteral implantation using a three‐stitch ureteroneocystostomy: description of technique and outcome in nine dogs

“…The only dog that experienced significant postoperative complications, dog 9, was diagnosed with concurrent follicular cystitis (Sul et al ). Follicular cystitis is a rare and non‐specific inflammatory disease of the bladder, primarily affecting women (Zaharopoulos , Trombella et al ).…”