Follicular Hyperkeratosis and Cryocrystalglobulinemia Syndrome

Lukitsch, Olinde; Gebhardt, Kurt-Peter; Kövary, Peter Michael

doi:10.1001/archderm.1985.01660060109033

Cited by 31 publications

(14 citation statements)

References 12 publications

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“…A linear arrangement of spicules can occasionally be seen. In most cases FH lesions have a nonfollicular distribution as in this case but some are found in association with underlying follicules 4,5 . As with our patient, involvement of only the palms has been described previously 1 …”

Section: Reportsupporting

confidence: 79%

“…FH is a rare disorder that has previously been referred to by different authors using a variety of different terms including hyperkeratotic spicules, 2,4 parakeratotic horns, follicular hyperkeratosis, 5 multiple minute digitate hyperkeratosis, minute aggregate keratosis, 3 punctate porokeratotic keratoderma and music box spine keratotic plugs. Multiple, thin, spiny, keratotic projections on the palms and soles or disseminated on various regions of the body are characteristic of the condition.…”

Section: Reportmentioning

confidence: 99%

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Palmar filiform hyperkeratosis (FH) associated with underlying pathology?

Mehta

Mallett

Green

et al. 2002

Clinical and Experimental Dermatology

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We describe two patients with palmar filiform hyperkeratosis, characterized by multiple thin spiny keratotic projections on the palms. The condition has been associated with an underlying malignancy in some cases. One patient has myelofibrosis, an association not previously described. In addition we describe a further patient with filiform hyperkeratoses of both palms and soles with no associated underlying disorder. In view of the relatively high risk of underlying malignancy occurring in patients with filiform hyperkeratosis, these patients should always be investigated fully.

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Section: Reportsupporting

confidence: 79%

Section: Reportmentioning

confidence: 99%

Palmar filiform hyperkeratosis (FH) associated with underlying pathology?

Mehta

Mallett

Green

et al. 2002

Clinical and Experimental Dermatology

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“…Treatments have not been reported in the literature. We favor the term ''postirradiation digitate keratosis'' over the synonymous terms presented in Table I, as this was the term first used when described by Burns 35 in 1986. Hyperkeratotic spicules [39][40][41][42][43][44][45][46][47] are follicular or nonfollicular digitate keratoses of the face (nose in particular), and may also involve the scalp, trunk, and limbs. They are often associated with paraproteinemia, multiple myeloma, and cryoglobulinemia, but may be idiopathic.…”

Section: Discussionmentioning

confidence: 99%

Multiple minute digitate hyperkeratosis: A proposed algorithm for the digitate keratoses

Caccetta

Dessauvagie

McCallum

et al. 2012

Journal of the American Academy of Dermatology

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“…Previous case reports did not describe the temporal relationship between the onset of cutaneous spicules with the disease activity of myeloma. There is, however, a strong suggestion of a close relation between both the hematologic disease and cutaneous manifestation, based on previous reports describing a resolution of the cutaneous lesions after treatment of the myeloma 3–5,19,20 …”

Section: Discussionmentioning

confidence: 99%