1934
DOI: 10.1001/archderm.1934.01460140003001
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Follicular Lesions in Vitamin a and C Deficiencies

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Cited by 30 publications
(2 citation statements)
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“…Their observations have been amply confirmed, and many descriptions of similar lesions seen in this country are now on record. [48][49][50][51][52][53] The early change is one of simple dryness (xeroderma).48,53 When more severe, according to Markowitz,54 the normal skin epithelium atrophies and is replaced by proliferating basal cells that become keratinized. A similar process in the skin glands and ducts causes accumulation of keratinized epithelium, which by protruding from the pilosebaceous follicular orifices results in the hyperkeratotic papules (hyperkeratosis follicularis) so characteristic of this disorder.…”
Section: Phrynodermamentioning
confidence: 99%
“…Their observations have been amply confirmed, and many descriptions of similar lesions seen in this country are now on record. [48][49][50][51][52][53] The early change is one of simple dryness (xeroderma).48,53 When more severe, according to Markowitz,54 the normal skin epithelium atrophies and is replaced by proliferating basal cells that become keratinized. A similar process in the skin glands and ducts causes accumulation of keratinized epithelium, which by protruding from the pilosebaceous follicular orifices results in the hyperkeratotic papules (hyperkeratosis follicularis) so characteristic of this disorder.…”
Section: Phrynodermamentioning
confidence: 99%
“…Preservation of the bag of waters is important in occipitoposterior positions if the head is high and the presenting part broad, as contraction and retraction are inefficient compared with the normal acutely flexed anterior occiput. 5. In the management there are three things to wait for.…”
Section: Diagnosismentioning
confidence: 99%