Follicular variant of papillary thyroid carcinoma arising from a dermoid cyst: A rare malignancy in young women and review of the literature

Abstract

Malignant transformation of a dermoid cyst is a rare ovarian neoplasm. We believe that unilateral oophorectomy or cystectomy is a reasonable treatment option for cases in which there is no evidence of capsular invasion, vascular invasion or gross metastasis, and preservation of fertility is desired. Total thyroidectomy was diagnosed in selected cases. Serial serum thyroglobulin should be used as a tumor marker for follow-up.

Successful in vitro fertilization pregnancy and delivery after a fertility-sparing laparoscopic operation in a patient with a papillary thyroid carcinoma arising from a mature cystic teratoma

“…Most reported cases of thyroid cancers in MCT are related to struma ovarii. Diverse treatment strategies have been reported, ranging from conservative surgery with the goal of preserving fertility to radical surgery, radiation, and chemotherapy with or without thyroidectomy [7][8][9][10][11][12][13][14][15]. Malignant struma ovarii commonly arises in the fifth decade of life; therefore, the mainstream treatment modality is hysterectomy with BSO [7][8][9][10][11][12][13][14][15].…”

“…Diverse treatment strategies have been reported, ranging from conservative surgery with the goal of preserving fertility to radical surgery, radiation, and chemotherapy with or without thyroidectomy [7][8][9][10][11][12][13][14][15]. Malignant struma ovarii commonly arises in the fifth decade of life; therefore, the mainstream treatment modality is hysterectomy with BSO [7][8][9][10][11][12][13][14][15]. Thyroidectomy, radioiodine treatment, and suppressive thyroid-stimulating hormone treatment are recommended as adjuvant therapy of struma ovarii [4,[7][8][9][10][11][12]15].…”

“…Malignant struma ovarii commonly arises in the fifth decade of life; therefore, the mainstream treatment modality is hysterectomy with BSO [7][8][9][10][11][12][13][14][15]. Thyroidectomy, radioiodine treatment, and suppressive thyroid-stimulating hormone treatment are recommended as adjuvant therapy of struma ovarii [4,[7][8][9][10][11][12]15]. However, adjuvant therapy remains controversial [7][8][9][10][11][12][13][14][15].…”

“…The treatment of thyroid cancer in an ovarian MCT is not well-defined because of its rarity [7][8][9][10][11][12]. Most reported patients have been treated with hysterectomy with unilateral or bilateral salpingo-oophorectomy (USO or BSO), fertility-preserving USO, or cystectomy, with or without total thyroidectomy [7][8][9][10][11][12]. There is no previous report of subsequent pregnancy after a fertility-preserving operation in a patient with this rare tumor.…”

Management and follow-up results of an incidental thyroid carcinoma in a young woman with ovarian teratoma

“…Patients follow-up with no further treatment (total thyroidectomy and radioactive iodine ablation) have great risk of recurrence, which is reported to be 15-38%. These patients should be evaluated for recurrent disease more frequently than the patients in whom complete ablation was succeeded [15]. It could be discussed that when postoperative MRI findings were absent, only thyroidectomy could be sufficient to safely follow-up patient [6].…”