Follicular Variant of Papillary Thyroid Carcinoma Presented as Autonomous Functioning Thyroid Nodule: A Case Report and Review of Literature

Shahbaz, Amir; Alkomos, Mina Fransawy; Mahendhar, Rupak; Nabi, Usman; Riaz, Maria; Sachmechi, Issac

doi:10.7759/cureus.3014

Cited by 2 publications

(1 citation statement)

References 13 publications

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“…34 However, there are at least eight case reports in the literature about patients with a follicular variant of papillary thyroid carcinoma as autonomous functioning thyroid nodule. 35 On the other hand, ATC was also reported in a long-standing multinodular goiter or a Hürthle cell tumor following RAI therapy. [36][37][38] This study has some limitations.…”

Section: Discussionmentioning

confidence: 99%

Dietary iodine intake, therapy with radioiodine, and anaplastic thyroid carcinoma

Bešič

Gazić

2020

Radiology and Oncology

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BackgroundAnaplastic thyroid cancer (ATC) is one of the most aggressive tumors. The aim of the study was to determine the correlation between a higher dietary intake of iodine, frequency of ATC and the characteristics of ATC, and to find out how often patients with ATC had a history of radioiodine (RAI) therapy.Patients and methodsThis retrospective study included 220 patients (152 females, 68 males; mean age 68 years) with ATC who were treated in our country from 1972 to 2017. The salt was iodinated with 10 mg of potassium iodide/ kg before 1999, and with 25 mg of potassium iodide/kg thereafter. The patients were assorted into 15-year periods: 1972–1986, 1987–2001, and 2002–2017.ResultsThe incidence of ATC decreased after a higher iodination of salt (p = 0.04). Patients are nowadays older (p = 0.013) and have less frequent lymph node metastases (p = 0.012). The frequency of distant metastases did not change over time. The median survival of patients in the first, second, and third periods was 3, 4, and 3 months, respectively (p < 0.05). The history of RAI therapy was present in 7.7% of patients.ConclusionsThe number of patients with a history of RAI therapy did not change statistically over time. The incidence of ATC in Slovenia decreased probably because of higher salt iodination.

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Section: Discussionmentioning

confidence: 99%

Dietary iodine intake, therapy with radioiodine, and anaplastic thyroid carcinoma

Bešič

Gazić

2020

Radiology and Oncology

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Clinical characteristics associated with the finding of thyroid cancer originating from hot nodules in patients with hyperthyroidism: a case report and systematic review of the literature

Osório¹,

Ballestas

Barrios

et al. 2021

Rev Colomb Cir

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Coexistence between thyroid cancer and hyperthyroidism is rare, and most of the nodular lesions from which a malignant tumor is documented in this group of patients correspond to cold nodules. Justified by the increasing number of reports in the literature about malignant tumors diagnosed from hot nodules, a systematic review was carried out to determine possible factors associated with the diagnosis of thyroid cancer from hot nodules in patients with hyperthyroidism. The results suggest that the clinical diagnosis of toxic nodular goiter, nodular lesions of diameter > 10 mm and a histological type compatible with a follicular carcinoma, are factors that on their own increase the risk of making the diagnosis of cancer from a hot nodule.

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Follicular Variant of Papillary Thyroid Carcinoma Presented as Autonomous Functioning Thyroid Nodule: A Case Report and Review of Literature

Cited by 2 publications

References 13 publications

Dietary iodine intake, therapy with radioiodine, and anaplastic thyroid carcinoma

Dietary iodine intake, therapy with radioiodine, and anaplastic thyroid carcinoma

Clinical characteristics associated with the finding of thyroid cancer originating from hot nodules in patients with hyperthyroidism: a case report and systematic review of the literature

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