Folliculo-Sebaceous Cystic Hamartoma

Requena, Luís; Sangüeza, Omar P.

doi:10.1007/978-3-319-45704-8_65

Cited by 1 publication

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“…Histopathologically, trichofolliculoma shows a dilated follicular structure with associated rudimentary follicles, but lacks a sebaceous component [6]. Moreover, sebaceous trichofolliculoma, considered a variant of trichofolliculoma, appears to show an even closer resemblance to folliculosebaceous cystic hamartoma because it displays a conspicuous sebaceous component [3]; sebaceous trichofolliculoma is characterized by a dilated follicular structure with rudimentary follicles associated with sebaceous glands, however, it is more superficially located; rudimentary follicles are connected with the cystic space, hair shafts are usually present within the follicular structures and a mesenchymal component is said to be absent [3,6]; these two lesions are very similar and have also been considered to represent a unique lesion [12].…”

Section: Discussionmentioning

confidence: 99%

Folliculosebaceous Cystic Hamartoma with Spindle Cell Lipomatous and Neural Components

Urso¹,

Yarygina²

2023

Dermatopathology

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Folliculosebaceous cystic hamartoma is a cutaneous malformation composed of a cystic folliculosebaceous structure associated with mesenchymal elements, generally consisting of fibrous stroma, adipocytes and small vascular channels. We report the case of a 55-year-old female patient with a cutaneous nodule of the right nasal wing. Microscopically, the lesion showed a dilated hair follicle with multiple sebaceous glands, surrounded by a mesenchymal component composed of fibromyxoid stroma, spindle cells, mature-appearing adipocytes and collagen bundles, resembling spindle cell lipoma, associated with an additional neural component, consisting of small nerve bundles. In folliculosebaceous cystic hamartoma, the association of spindle cell lipomatous and neural components has not previously reported.

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