Folliculotropic Mycosis Fungoides

També, Swagata; Zambare, Uddhao; Nayak, Chitra

doi:10.4103/idoj.idoj_289_20

Cited by 3 publications

(15 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Additional histological findings include follicular mucinosis, Pautrier's micro-abscess, follicular plugging, atypical lymphocytes residing along the basal layers of the follicular epithelium, and perieccrine infiltration of atypical lymphocytes. 22,25 Immunohistochemistry usually shows a prominent CD3positive T-cell infiltrate, with a predominance of CD4positive T lymphocytes over rare CD8-positive T cells. CD7 expression may be reduced or even completely lost.…”

Section: Studiesmentioning

confidence: 99%

“…Molecular analysis (T cell receptor-γ gene rearrangement) may show monoclonal T cells. 22,[25][26][27] Treatment options for F-MF include photochemotherapy in combination with interferon alpha-2a and retinoids. Other options include local radiotherapy, topical imiquimod, and wholebody electron irradiation.…”

Section: Studiesmentioning

confidence: 99%

“…25 The lesions of F-MF can be solitary or extensive leading to the appearance of a leonine face. 22 Pruritis is a common complaint that may be aggravated by staphylococcal auras infection resulting in pyoderma. 24 In F-MF, the head and neck area is the most affected region.…”

Section: Studiesmentioning

confidence: 99%

“…Other F‐MF lesions may resemble rosacea or lupus tumidus 25 . The lesions of F‐MF can be solitary or extensive leading to the appearance of a leonine face 22 . Pruritis is a common complaint that may be aggravated by staphylococcal auras infection resulting in pyoderma 24 …”

Section: Introductionmentioning

confidence: 99%

“…Treatment options for F‐MF include photochemotherapy in combination with interferon alpha‐2a and retinoids. Other options include local radiotherapy, topical imiquimod, and whole‐body electron irradiation 22 …”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Folliculotropic mycosis fungoides associated with follicular mucinosis: A case report and mini review

Aldayhum,

Alshahrani,

Hussein

et al. 2024

Clinical Case Reports

View full text Add to dashboard Cite

Key Clinical MessageF‐MF is a rare non‐classic variant of MF. In the case of hair loss, this should be a diagnostic consideration. The essence of the diagnosis of F‐MF is a careful medical history, physical examination, and a combination of immunohistological and molecular analyses (Cureus. 2022; 14:e21231, Ann Saudi Med. 2012; 32:283, Oman Med J. 2012; 27:134, Int J Dermatol. 2016; 55:1396, Saudi Med J. 2018; 39:994 and Case Rep Oncol. 2018; 11:436).AbstractMycosis fungoides (MF) is a primary cutaneous T‐cell lymphoma with multiple subtypes. Follicular MF (F‐MF) is a non‐classic variant of MF. Histological features entail folliculotropism and damage of the epithelium lining of the hair follicles with or without mucin deposition. A 52‐year‐old male patient complained of recurrent skin lesions on the scalp over 8 months. The lesions appeared suddenly, enlarged over time, and became itchy. A skin punch biopsy was performed. Histological features included mucin deposits in the epithelium of the hair follicles and dense, predominantly perifollicular atypical lymphocytes infiltrating the follicular epithelium. The lymphoid cells were composed of CD3‐positive T cells (CD4/CD8‐positive T cells) with a shift in favor of the former. The case was diagnosed as F‐MF on an immunohistological basis. The diagnosis of F‐MF is often difficult for dermatologists and dermatopathologists alike. Not only clinicopathological correlations but also immunohistochemical and molecular analysis are required.

show abstract

Section: Studiesmentioning

confidence: 99%

Section: Studiesmentioning

confidence: 99%

Section: Studiesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Folliculotropic mycosis fungoides associated with follicular mucinosis: A case report and mini review

Aldayhum,

Alshahrani,

Hussein

et al. 2024

Clinical Case Reports

View full text Add to dashboard Cite

show abstract

Folliculotropic mycosis fungoides associated with follicular mucinosis: a case report and minireview

Aldayhum,

Alshahrani,

Hussein

et al. 2023

Preprint

View full text Add to dashboard Cite

Folliculotropic mycosis fungoides in a child: a rare case

Fatima Zahoor,

Junaid,

Ghazal Afzal

2023

J Pak Med Assoc

View full text Add to dashboard Cite

Folliculotropic mycosis fungoides (FMF) is a variant of mycosis fungoides characterized by infiltration of hair follicle epithelium by neoplastic lymphoid cells. Generally, it is usually typified by indurated plaques and tumours mainly on the head and neck. However, a wide range of clinical signs have been noted. The clinical presentation of FMF may include prurigo-like lesions, acneiform lesions, cysts, nodules, areas of scarring alopecia, and hypopigmented plaques or papules with follicular prominences. The average age of diagnosis is 60 years while it is rare in childhood and adolescence. We discuss the case of a 12-year-old boy patient who had an asymptomatic, erythematous, infiltrating plaque across his left nasolabial fold for three months prior to presentation. Histological assessment of lesion showed characteristic findings of follicular mucinosis with predominance of CD4+ lymphocytes and immunohistochemical studies were positive for CD3+ stains. An increased CD4:CD8 ratio and negative CD20 was also shown. ---Continue

show abstract

Folliculotropic Mycosis Fungoides

Cited by 3 publications

References 12 publications

Folliculotropic mycosis fungoides associated with follicular mucinosis: A case report and mini review

Folliculotropic mycosis fungoides associated with follicular mucinosis: A case report and mini review

Folliculotropic mycosis fungoides associated with follicular mucinosis: a case report and minireview

Folliculotropic mycosis fungoides in a child: a rare case

Contact Info

Product

Resources

About