“…1 Several published reports have demonstrated that in a high percentage of cases the histological results of CB concur with those obtained from the examination of the whole of the excised specimen. [3][4][5][6][7][8][9] Furthermore, CB provides an extremely high level of diagnostic reliability, not only with regard to cases of infiltrating carcinoma, but also to those involving atypical hyperplasia, lobular carcinomas in situ, [10][11][12][13][14][15][16] (DCIS) 4,5,8,11,14,16,17 and to a large number of benign breast diseases. 18,19 Although CB has not completely replaced traditional excisional biopsy, it is considered to be a valid diagnostic procedure, since it is not only efficient but also well tolerated and not particularly invasive, making it possible for the surgeon to provide the patient with a great deal of information regarding her disease and to plan a more specific therapeutic approach.…”