Follow-up Study of Dental Implants With Bioactive Oxide Films on Bone Tissue Healing and Osseointegration

Chiang, Hsi Jen; Cheng, Han; Ou, Keng Liang; Sinrang, Andi Wardihan; Huang, Maosong; Lin, Li Hsiang

doi:10.1097/id.0000000000000181

Cited by 1 publication

(2 citation statements)

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“…A previous study demonstrated that a SLAffinity specimen had an obviously thicker oxide layer (~500 nm) on the surface. The specific surface characteristics of a SLAffinity specimen improved wettability and promoted cell proliferation, adhesion, and spreading [ 14 , 17 ]. In the present study, the SLAffinity group presented a larger area of the bone-screw interface, as well as more osteogenic cells and new bone formation at the peri-implant tissue, which may result from the superior surface properties of this implant.…”

Section: Discussionmentioning

confidence: 99%

“…We previously applied a novel surface modification called SLAffinity to dental implants. With grit-blasted and acid-etched treated by electrochemical functionalization, a SLAffinity-Ti surface had a 500-nm oxide layer deep inside the Ti structure [ 14 ]. This structure showed high biocompatibility and wettability, allowing ready adhesion to blood.…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of osseous integration of titanium orthopedic screws with novel SLA treatment in porcine model

Lin

Hu²,

Wang

et al. 2017

PLoS ONE

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The success of many endosseous implants in orthopaedic and dental applications depends on the surface characteristics, as they affect osseous integration. Previous investigations indicated that a novel large-grit sand-blasted and acid-etched (SLA) titanium (denoted as SLAffinity-Ti) implant had better bone integration than that of a comparably shaped implant with a plasma-sprayed titanium surface. The purpose of the present investigation was to create a SLAffinity surface on pedicle screws and trauma screws and to compare it with the surfaces of a sand-blasted-only implant and commercial implants in terms of bone integration. The cortical bone and spine of twelve minipigs were implanted with 3 and 4 implants, respectively, and the bone integration was evaluated using micro-computed tomography (micro-CT), mechanical tests (pull-out strength and stripping torque), and histological analysis (toluidine blue and hematoxylin and eosin staining) one and three months after implantation. The micro-CT images showed that the gap between the bone and implant was consistently higher in the sand-blasted-only and commercial groups compared to that in the SLAffinity group 1 and 3 months after implantation. Moreover, the bone volume of implant inserted into bone and the percentage of implant inside bone tissue were greater in the SLAffinity screws 1 and 3 months after implantation, as compared to the sand-blasted and commercial screws. In the mechanical tests, the removal torque and pull-out strength (p < 0.05) were higher in the SLAffinity group at 1 and 3 months. The histological results were consistent with mechanical testing, showing that the SLAffinity group had the most mineralized matrix, the most bone formation around the screws, and the most bone cells in bone tissue. These findings indicate that a SLAffinity surface can effectively enhance the holding strength and integration of pedicle screws and cortical screws, promoting early healing and improving outcomes, compared to sand-blasted-only and commercial implants.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Evaluation of osseous integration of titanium orthopedic screws with novel SLA treatment in porcine model

Lin

Hu²,

Wang

et al. 2017

PLoS ONE

View full text Add to dashboard Cite

show abstract

Follow-up Study of Dental Implants With Bioactive Oxide Films on Bone Tissue Healing and Osseointegration

Abstract: The results confirmed that functional films could improve the biomechanical properties of the implants and promote the initial bone stability. Furthermore, potential clinical benefit can be obtained due to the inducing superior biomechanical behavior in dental implants.

Cited by 1 publication

References 28 publications

Evaluation of osseous integration of titanium orthopedic screws with novel SLA treatment in porcine model

Evaluation of osseous integration of titanium orthopedic screws with novel SLA treatment in porcine model

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