Follow-Up Survey of Japanese Encephalitis Virus Infection in Kumamoto Prefecture, South-West Japan: Status during 2009^|^ndash;2011

Konishi, Eiji; Kitai, Yoko; Nishimura, Koichi; Harada, Seiya

doi:10.7883/yoken.65.448

Cited by 8 publications

(7 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…One should note that in order to eliminate an interference effect of BSA in immunoassay, the concentration has to be less than or equal to 1% of the NS1 antigen amount (Konishi et al 2010). For control experiments, separate SPGEs were conjugated with mouse IgG 0.1 mg/mL (Pierce, Cat.…”

Section: Instrumentsmentioning

confidence: 99%

Electrochemical lateral flow immunosensor for detection and quantification of dengue NS1 protein

Sinawang

Rai

Ionescu

et al. 2016

Biosensors and Bioelectronics

138

View full text Add to dashboard Cite

Section: Instrumentsmentioning

confidence: 99%

Electrochemical lateral flow immunosensor for detection and quantification of dengue NS1 protein

Sinawang

Rai

Ionescu

et al. 2016

Biosensors and Bioelectronics

138

View full text Add to dashboard Cite

“…JEV is still prevalent in South-East Asia and South Asia. The number of reported cases markedly decreased to less than 10 patients in one year recently in Japan [ 23 ]. Antibodies and CTL are both considered to protect against JEV infection based on the findings of animal experiments using the artificial transfer of sera and CTL.…”

Section: Discussionmentioning

confidence: 99%

Recombinant Measles AIK-C Vaccine Strain Expressing the prM-E Antigen of Japanese Encephalitis Virus

et al. 2016

View full text Add to dashboard Cite

An inactivated Japanese encephalitis virus (JEV) vaccine, which induces neutralizing antibodies, has been used for many years in Japan. In the present study, the JEV prM-E protein gene was cloned, inserted at the P/M junction of measles AIK-C cDNA, and an infectious virus was recovered. The JEV E protein was expressed in B95a cells infected with the recombinant virus. Cotton rats were inoculated with recombinant virus. Measles PA antibodies were detected three weeks after immunization. Neutralizing antibodies against JEV developed one week after inoculation, and EIA antibodies were detected three weeks after immunization. The measles AIK-C-based recombinant virus simultaneously induced measles and JEV immune responses, and may be a candidate for infant vaccines. Therefore, the present strategy of recombinant viruses based on a measles vaccine vector would be applicable to the platform for vaccine development.

show abstract

“…Recently, dengue infections have increased in Japan among people traveling to endemic areas [ 13 ]. Japanese encephalitis (JE) is almost the only endemic flavivirus disease in Japan, particularly in southern regions [ 14 , 15 ]. An estimated 2% of the population are believed to have been naturally infected with JEV.…”

Section: Discussionmentioning

confidence: 99%

Dengue Hemorrhagic Fever in a Japanese Traveler with Pre-existing Japanese Encephalitis Virus Antibody

Sato¹,

Hamada

Kashiwagi

et al. 2015

Trop.Med.Health

View full text Add to dashboard Cite

An adult Japanese man who had just returned from Thailand developed dengue hemorrhagic fever (DHF). A primary infection of dengue virus (DENV) was confirmed, specifically DENV serotype 2 (DENV-2), on the basis of the detection of the virus genome, a significant increase in the neutralizing antibody and the isolation of DENV-2. DHF is often observed following a secondary infection from another serotype of dengue virus, particularly in children, but this case was a primary infection of DENV. Japan is a non-endemic country for dengue disease. In fact, only Japanese encephalitis (JE) is known to be a member of the endemic flavivirus family. In this study, IgG antibody against Japanese encephalitis virus (JEV) was detected. JEV belongs to the family of dengue virus and prevails in Japan, particularly Kyushu. Among many risk factors for the occurrence of DHF, a plausible candidate could be a cross-reactive antibody-dependent enhancement (ADE) mechanism caused by JEV antibody. This indicates that most Japanese travelers who living in dengue non-endemic areas, particularly Kyushu, should be aware of the occurrence of DHF.

show abstract

Follow-Up Survey of Japanese Encephalitis Virus Infection in Kumamoto Prefecture, South-West Japan: Status during 2009^|^ndash;2011

Cited by 8 publications

References 8 publications

Electrochemical lateral flow immunosensor for detection and quantification of dengue NS1 protein

Electrochemical lateral flow immunosensor for detection and quantification of dengue NS1 protein

Recombinant Measles AIK-C Vaccine Strain Expressing the prM-E Antigen of Japanese Encephalitis Virus

Dengue Hemorrhagic Fever in a Japanese Traveler with Pre-existing Japanese Encephalitis Virus Antibody

Contact Info

Product

Resources

About