Food and drug allergy, and anaphylaxis in EAACI journals (2018)

Eigenmann, Philippe; Akdiş, Cezmi A.; Bousquet, Jean; Grattan, Clive; Hoffmann‐Sommergruber, Karin; Jutel, Marek

doi:10.1111/pai.13125

Cited by 12 publications

(5 citation statements)

References 86 publications

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“…If any reactions suspicious of FA were reported, the children were to be brought to the hospital for appropriate management immediately. OFC results were used as diagnostic criterion for FA 13 in accordance with the EAACI guidelines, 14 which has depicted in more detail in a previous article 12 . Any participant with an incomplete diagnostic process was considered a dropout.…”

Section: Methodsmentioning

confidence: 99%

Time trends of childhood food allergy in China: Three cross‐sectional surveys in 1999, 2009, and 2019

Lin

Xian

et al. 2021

Pediatric Allergy Immunology

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Background Many countries have recorded the trends of food allergy (FA) prevalence. Little is known about epidemiologic trends of childhood FA in China. Methods In three cross‐sectional surveys conducted in 1999, 2009, and 2019, the prevalence of and characteristic changes in FA in children aged ≤ 2 years were assessed and the outcomes were compared. All the children were recruited during well‐baby check‐ups at the Children's Hospital of Chongqing Medical University. All participants had a detailed medical history taken and underwent skin prick tests using ten commercial food extracts. Open food challenges were used for confirmation of FA. Results The three studies included 1228 children (314 in 1999, 401 in 2009, and 513 in 2019; response rate > 95%). The prevalence of FA in 2009 (7.7%) and 2019 (11.1%) was significantly higher than that in 1999 (3.5%). However, there was no statistically significant difference in prevalence between 2009 and 2019 (P = .086). There was evidence of increased prevalence in CMPA between 1999 and 2019 (1.6% versus 5.7%; P = .004). However, no statistic difference was found in egg allergy (2.9% versus 5.5%; P = .21). The incidence of skin symptoms did not differ significantly over the study period, while the incidence of gastrointestinal symptoms increased significantly (18.2% in 1999, 12.9% in 2009, and 43.9% in 2019; P < .05). Conclusions The prevalence of FA in children rapidly increased after the 1990s and gradually stabilized after 2010. Cow's milk has become the most common food allergen among children in Chongqing. The incidence of gastrointestinal symptoms as a manifestation of FA has increased significantly since 2010.

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Section: Methodsmentioning

confidence: 99%

Time trends of childhood food allergy in China: Three cross‐sectional surveys in 1999, 2009, and 2019

Lin

Xian

et al. 2021

Pediatric Allergy Immunology

View full text Add to dashboard Cite

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“…Parents were asked to report any symptoms that occurred in the following at least 3 days. If any reactions suspicious of EA were reported, the children were to be brought to the hospital for appropriate manageent immediately inaccordance with the EAACI guidelines 13 .And next,the egg white OFC was performed again after elimination of whole egg for 2 weeks..Any participant with an incomplete diagnostic process was considered a dropout.The symptoms were improved after avoidance, and the symptoms reappeared as OFC positive after re-intake, and the diagnosis of egg allergy was established. On the contrary, it is negative.…”

Section: Oral Food Challengesmentioning

confidence: 99%

Predictive factors of egg allergy clinical outcomes in infants and young children

Shao

2022

Preprint

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Aim: The aim of the present study was to explore the tolerance march in children and establish probable factors that affect the prognosis of an egg allergy (EA). Methods: Two hundred children 6 months to 2.5 years old with atopic dermatitis (AD) were recruited into our study from 2018 to 2019. EA was diagnosed based on medical history, the skin prick test (SPT), and the oral food challenge test (OFC) ,EA was diagnosed in 78，among those, 7 were allergic only to egg yolk (OnlyEYA), 20 to egg white (OnlyEWA), and 51 to whole egg (WEA). Logistic regression analysis was used to detect the disease course and related risk factors of outcomes. The receiver operating characteristic curve was used to establish a predicting model. Results:The Scoring Atopic Dermatitis score in the WEA group was more severe and persistent than that in the other groups. Forty-three cases of EA developed clinical tolerance (average age, 32.3 ± 8.7 months). The tolerance rate of EYA was 75.9% and EWA was 56.3%. The SPT wheal diameter at initial diagnosis (SPT ) was the risk factor for persistent EA. The SPT wheal diameter after 6 months (△SPT ) in the tolerant group decreased markedly compared to that in the persistent EA group. Tolerance was higher when △EW-SPT ≥ 39.5% or △EY-SPT ≥ 27%. Conclusion: The initial SPT and SPT values were significantly correlated with and can predict outcomes of EA. Key words: Egg allergy, atopic dermatitis, outcome, related factors.

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“…Parents were asked to report any symptoms that occurred in the subsequent 3 days. In case of occurrence of any reactions suspicious of EA, the children were to be brought to the hospital immediately for appropriate management in accordance with the EAACI guidelines 13 .Next, the egg white OFC was performed again after elimination of whole egg for 2 weeks. Any participant with an incomplete diagnostic process was considered a dropout.…”

Section: Oral Food Challengesmentioning

confidence: 99%

Predictive factors of egg allergy clinical outcomes in infants and young children

Shao

2022

Preprint

View full text Add to dashboard Cite

Aim: To explore the tolerance march in children and identify potential factors that affect the prognosis of egg allergy (EA). Methods: Two hundred children(age range, 6 months-2.5 years)with atopic dermatitis (AD) were recruited from 2018 to 2019. EA was diagnosed based on medical history, skin prick test (SPT), and the oral food challenge (OFC) test. EA was diagnosed in 78 children; among these, 7 were allergic only to egg yolk (Only EYA), 20 to egg white (Only EWA), and 51 to whole egg (WEA). Logistic regression analysis was used to identify risk factors for outcomes during the disease course. Receiver operating characteristic (ROC) curve analysis was performed to establish a predicting model. Results: The Scoring Atopic Dermatitis score in the WEA group was more severe and persistent than that in the other groups. Forty-three cases of EA developed clinical tolerance (average age, 32.3 ± 8.7 months). The tolerance rate of EYA and EWA was 75.9% and 56.3%, respectively. The SPT wheal diameter at initial diagnosis (SPTdiag) was a risk factor for persistent EA. The SPT wheal diameter after 6 months (△SPT6mo) in the tolerant group was markedly decreased compared to that in the persistent EA group. Tolerance was higher when △EW-SPT6mo ≥ 39.5% or △EY-SPT6mo ≥ 27%. Conclusion: The initial SPTdiag and SPT6mo values were significantly correlated with and can predict outcomes of EA.

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Food and drug allergy, and anaphylaxis in EAACI journals (2018)

Cited by 12 publications

References 86 publications

Time trends of childhood food allergy in China: Three cross‐sectional surveys in 1999, 2009, and 2019

Time trends of childhood food allergy in China: Three cross‐sectional surveys in 1999, 2009, and 2019

Predictive factors of egg allergy clinical outcomes in infants and young children

Predictive factors of egg allergy clinical outcomes in infants and young children

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