Edible energy harvesting merges food science, biotechnology, and engineering to convert chemical energy from safe, ingestible substances into electrical power. This chapter explores the evolution of energy harvesting technologies, focusing on advancements in materials science and biocompatible electronics. It discusses the significance of edible energy harvesting in medical devices, sustainable technologies, and IoT applications. Safety and ethical considerations, along with recent innovations in fabrication techniques and regulatory frameworks, are analyzed. The chapter concludes with prospects for integrating energy harvesting components into food and addressing challenges for broader adoption in healthcare and environmental sustainability. Ethical and environmental considerations, including safety and biocompatibility, are crucial in advancing these technologies. The chapter also discusses challenges such as regulatory compliance and environmental impact mitigation, highlighting the pathway for future developments in edible energy harvesting.