Food-derived peptides as novel therapeutic strategies for NLRP3 inflammasome-related diseases: a systematic review

Zhang, Ziqi; Zhang, Yuan; Zhang, Meiying; Yu, Chenfeng; Yang, Pingping; Xu, Minxuan; Ling, Jitao; Wu, Yuting; Zhu, Zicheng; Chen, Yixuan; Shi, Ao; Liu, Xiao; Zhang, Jing; Yu, Peng; Zhang, Deju

doi:10.1080/10408398.2023.2294164

Cited by 2 publications

(1 citation statement)

References 310 publications

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“…Fats have many functional properties in a food carrier as they play a signi cant role in the texture, color, and sensory properties of foods in many speci c ways [1]. However, excessive consumption of fat is related to a lot of health risks, such as obesity, atherosclerosis, hypertension, diabetes, in ammation, gall bladder disease, and cancer [2][3][4][5]; this has aroused the concern of consumers that dietary fat intake should be tightly controlled to reduce the risk of multiple diseases [6]. Driven by the expansion of the pizza industry, Mozzarella cheese sales achieve substantial growth and currently become the most commonly purchased cheese in the US [7].…”

Section: Introductionmentioning

confidence: 99%

Effect of pre-acidification and whey proteins on low-fat Mozzarella cheese during storage: physicochemical, textural, and functional properties

Zhang,

Xiong,

Jiang

et al. 2024

Preprint

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The aim of the current study was to explore the effect of pre-acidification and whey protein-based fat replacers (CH-4560 and YO-8075) on low-fat Mozzarella cheese (LFC). The color and browning, calcium, meltability, texutre and pizza bake performance of cheeses at 0, 7, 14, 21, 28 days storage was determined, and full-fat cheeses (FFC; milk containing 2.21 g fat/100 g milk) and LFC were manufactured as control. The LFC without fat replacer was harder, less sticky, and had high stretch force and low meltability, as well as poor pizza bake and stretch performance, while these appearance defects were partially corrected via the addition of whey protein concentrates and using pre-acidification. Pre-acidification of cheese milk to pH 5.5 or lower negatively affected the stickiness, and pizza bake, and stretch performance of LFC and LFC with fat replacers. As aging progressed, the meltability, stickiness and stretch performance of Mozzarella cheese improved, whereas the hardness and stretch force of Mozzarella cheese decreased. Our study will provide guidance for the preparation of higher quality low-fat mozzarella cheese.

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Section: Introductionmentioning

confidence: 99%

Effect of pre-acidification and whey proteins on low-fat Mozzarella cheese during storage: physicochemical, textural, and functional properties

Zhang,

Xiong,

Jiang

et al. 2024

Preprint

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Anti-breast cancer effects of dairy protein active peptides, dairy products, and dairy protein-based nanoparticles

Zhang,

Yuan,

Xiong

et al. 2024

Front. Pharmacol.

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Breast cancer is the most frequently diagnosed and fatal cancer among women worldwide. Dairy protein-derived peptides and dairy products are important parts of the daily human diet and have shown promising activities in suppressing the proliferation, migration, and invasion of breast cancer cells, both in vitro and in vivo. Most of the review literature employs meta-analysis methods to explore the association between dairy intake and breast cancer risk. However, there is a lack of comprehensive summary regarding the anti-breast cancer properties of dairy protein-derived peptides, dairy products, and dairy protein-based nanoparticles as well as their underlying mechanisms of action. Therefore, the present study discussed the breast cancer inhibitory effects and mechanisms of active peptides derived from various dairy protein sources. Additionally, the characteristics, anti-breast cancer activities and active components of several types of dairy products, including fermented milk, yogurt and cheeses, were summarized. Furthermore, the preparation methods and therapeutic effects of various dairy protein-containing nanoparticle delivery systems for breast cancer therapy were briefly described. Lastly, this work also provided an overview of what is currently known about the anti-breast cancer effects of dairy products in clinical studies. Our review will be of interest to the development of natural anticancer drugs.

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Food-derived peptides as novel therapeutic strategies for NLRP3 inflammasome-related diseases: a systematic review

Cited by 2 publications

References 310 publications

Effect of pre-acidification and whey proteins on low-fat Mozzarella cheese during storage: physicochemical, textural, and functional properties

Effect of pre-acidification and whey proteins on low-fat Mozzarella cheese during storage: physicochemical, textural, and functional properties

Anti-breast cancer effects of dairy protein active peptides, dairy products, and dairy protein-based nanoparticles

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