“…While fluorescence imaging in the NIR-II window benefits from increased depth penetration, minimized tissue scattering, and diminished autofluorescence [9] , PAI is also appealing since it relies on ultrasound (US) detection for image reconstruction, enabling imaging at much greater depths. A wide range of contrast agents have been employed for PAI [10] , [11] , [12] , [13] , [14] , [15] , [16] , [17] .…”