Food-Grade Emulsions and Emulsion Gels Prepared by Soy Protein–Pectin Complex Nanoparticles and Glycyrrhizic Acid Nanofibrils

Li, Qing; He, Qixin; Xu, Mingang; Li, Junguang; Liu, Xiao; Wan, Zhinian; Yang, Xiaoquan

doi:10.1021/acs.jafc.9b04957

Cited by 86 publications

(34 citation statements)

References 59 publications

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“…When the concentration of LAE was between 0.0075% and 0.02%, the three-phase contact angle of the LAE/NMMT complex was approximately 90˚, which indicated that the LAE/NMMT complex had stronger amphiphilic property and better emulsifying ability. It was consistent with the microscopic observation [24]. The oil-water contact angle, measured through water in the oil phase having strong polarity, was larger, and the particles combined more easily at the oil-water interface, which was beneficial to the formation and stability of oil-in-water Pickering emulsions [25].…”

Section: Pickering Emulsion Stabilised By Lae/nmmtsupporting

confidence: 89%

Electrostatic Complexes of Nano-Montmorillonite/Ethyl Lauroyl Arginate Stabilized Sunflower Oil Pickering Emulsions

Luo¹,

Jing²,

Yang³

et al. 2022

MSCE

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Compared with traditional surfactant-stabilised emulsions, Pickering emulsions, stabilised by clay nanoparticles, have the advantages of strong interface stability, strong versatility, and low toxicity. Moreover, they have excellent application potential in the fields of food and medicine. In this study, a food-grade Pickering emulsion stabiliser was prepared by physically adsorbing the cationic surfactant ethyl lauroyl arginate (LAE) on the surface of nano-montmorillonite (NMMT). Different LAE/NMMT combinations were assessed for their capacity to stabilise an oil-in-water emulsion at a low solid concentration (0.5%, w/v). The controllability of the droplet diameter and stability of the Pickering emulsions can be realised by changing the content of LAE. Scanning electron microscopy (SEM), and laser confocal microscopy (CLSM) confirmed the successful preparation of sunflower oil Pickering emulsion droplets stabilised by LAE/NMMT (0.0075%/1%). Additionally, the LAE/NMMT studied in this work could be used as a highly effective antibacterial surfactant with inorganic nanoparticles to efficiently stabilise Pickering emulsions, thus expanding the potential of preparing edible Pickering emulsion formulae.

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Section: Pickering Emulsion Stabilised By Lae/nmmtsupporting

confidence: 89%

Electrostatic Complexes of Nano-Montmorillonite/Ethyl Lauroyl Arginate Stabilized Sunflower Oil Pickering Emulsions

Luo¹,

Jing²,

Yang³

et al. 2022

MSCE

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“…A prerequisite for a qualified stabilizer of Pickering emulsion systems is the partial wettability in both oil and water phases. The wettability of OVT fibrils/spheres in oil and water phases was reflected by a three-phase contact angle (oil–water-solid) to verify if it was a qualified stabilizer of OPEs [ 36 ]. Figure 2 shows that the three-phase contact angles of OVT fibrils and OVT spheres were 84.8° and 80.2°, respectively.…”

Section: Resultsmentioning

confidence: 99%

Fibrous and Spherical Aggregates of Ovotransferrin as Stabilizers for Oleogel-Based Pickering Emulsions: Preparation, Characteristics and Curcumin Delivery

Zhou

Wei

et al. 2022

Gels

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This study aimed to explore the effects and mechanisms of differently shaped aggregates of ovotransferrin (OVT) particles on oleogel-based Pickering emulsions (OPEs). Medium-chain triglyceride oil-based oleogels were constructed using beeswax, and their gel-sol melting temperatures were investigated. Atomic force microscopy confirmed that both OVT fibrils and OVT spheres were successfully prepared, and the three-phase contact angle measurements indicated that fibrous and spherical aggregates of OVT particles possessed great potential to stabilize the OPEs. Afterward, the oil-in-water OPEs were fabricated using oleogel as the oil phase and OVT fibrils/spheres as the emulsifiers. The results revealed that OPEs stabilized with OVT fibrils (FIB-OPEs) presented a higher degree of emulsification, smaller droplet size, better physical stability and stronger apparent viscosity compared with OPEs stabilized with OVT spheres (SPH-OPEs). The freeze–thaw stability test showed that the FIB-OPEs remained stable after three freeze–thaw cycles, while the SPH-OPEs could barely withstand one freeze–thaw cycle. An in vitro digestion study suggested that OVT fibrils conferred distinctly higher lipolysis (46.0%) and bioaccessibility (62.8%) of curcumin to OPEs.

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“…The self-assembling of GLR into a fibrillar network leads to the formation of micro-structures (Fig. 4) with specific mechanical properties (Li et al, 2020;Wan et al, 2018). The self-assembly of supramolecular GLR nanofibrils can be exploited to form ultrastable, thermostimulable, and processable foams (Ma et al, 2019).…”

Section: Improved Glr Formulation For In Vivo Administrationsmentioning

confidence: 99%

Glycyrrhizin: An alternative drug for the treatment of COVID-19 infection and the associated respiratory syndrome?

Bailly

Vergoten

2020

Pharmacology & Therapeutics

252

205

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Safe and efficient drugs to combat the current COVID-19 pandemic are urgently needed. In this context, we have analyzed the anti-coronavirus potential of the natural product glycyrrhizic acid (GLR), a drug used to treat liver diseases (including viral hepatitis) and specific cutaneous inflammation (such as atopic dermatitis) in some countries. The properties of GLR and its primary active metabolite glycyrrhetinic acid are presented and discussed. GLR has shown activities against different viruses, including SARS-associated Human and animal coronaviruses. GLR is a non-hemolytic saponin and a potent immuno-active anti-inflammatory agent which displays both cytoplasmic and membrane effects. At the membrane level, GLR induces cholesterol-dependent disorganization of lipid rafts which are important for the entry of coronavirus into cells. At the intracellular and circulating levels, GLR can trap the high mobility group box 1 protein and thus blocks the alarmin functions of HMGB1. We used molecular docking to characterize further and discuss both the cholesterol-and HMG boxbinding functions of GLR. The membrane and cytoplasmic effects of GLR, coupled with its long-established medical use as a relatively safe drug, make GLR a good candidate to be tested against the SARS-CoV-2 coronavirus, alone and in combination with other drugs. The rational supporting combinations with (hydroxy)chloroquine and tenofovir (two drugs active against SARS-CoV-2) is also discussed. Based on this analysis, we conclude that GLR should be further considered and rapidly evaluated for the treatment of patients with COVID-19.

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Food-Grade Emulsions and Emulsion Gels Prepared by Soy Protein–Pectin Complex Nanoparticles and Glycyrrhizic Acid Nanofibrils

Cited by 86 publications

References 59 publications

Electrostatic Complexes of Nano-Montmorillonite/Ethyl Lauroyl Arginate Stabilized Sunflower Oil Pickering Emulsions

Electrostatic Complexes of Nano-Montmorillonite/Ethyl Lauroyl Arginate Stabilized Sunflower Oil Pickering Emulsions

Fibrous and Spherical Aggregates of Ovotransferrin as Stabilizers for Oleogel-Based Pickering Emulsions: Preparation, Characteristics and Curcumin Delivery

Glycyrrhizin: An alternative drug for the treatment of COVID-19 infection and the associated respiratory syndrome?

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