Food hypersensitivity reactions in atopic dermatitis patients and analysis of contomitant diseases

Abstract

Only few population-based data exist on the association of food hypersensitivity reactions and atopic diseases. The objective of this study was to evaluate the dependence between the occurrence of food hypersensitivity reactions and other atopic diseases and parameters. Complete dermatological and allergological examination was performed. Statistical evaluation of the relations between the occurrence of food hypersensitivity reactions and the occurrence of asthma bronchiale, rhinitis, duration of atopic dermatitis, family history and onset of atopic dermatitis was performed. Two hundred and thirty-five patients were examined -75 men and 160 women, average age 26.2 years (SD = 9.5). Patients suffering from food hypersensitivity reactions, in general, suffer significantly more often from rhinitis and from persistent eczematic lesions; the dependence was confirmed in patients with hypersensitivity reactions to nuts, kiwi, fishes and apple. Atopic march was confirmed in patients suffering from atopic dermatitis and from food hypersensitivity reactions.

Atopic march, food allergy and food hypersensitivity in children and adolescents suffering from atopic dermatitis

“…According to our results, adolescent and adult patients suffering from food hypersensitivity reactions in general suffer significantly more often from rhinitis and from persistent eczematic lesions; the dependence was confirmed in patients with hypersensitivity reactions to nuts, kiwi, fishes and apple (Celakovská & Bukac, 2015). Regarding the role of food allergy in atopic march, AD patients with confirmed food allergy suffer significantly more often from rhinitis, asthma bronchiale, persistent eczematic lesions, pollen allergy and have positive data about atopy in their family history.…”

“…According to our results, challenge-proven food allergy was rare (wheat 2.2%, egg 5%, and cow's milk 1%) whereas 11.2% showed allergic sensitization to wheat, 20% to egg, and 10% to cow's milk. (Celakovská & Bukac, 2015;Celakovská, Ettlerova, Ettler, & Vaneckova, 2011).…”

Atopic dermatitis in adolescents and adults – the evaluation of association with other allergic diseases and parameters

“…The occurrence of food hypersensitivity reactions and the relation to the occurrence of bronchial asthma, allergic rhinitis, family history of atopy, onset of AD and persistent lesions of AD. Atopic march was confirmed in patients suffering from AD and from food hypersensitivity reactions (Celakovska, Bukac, & Ettler, 2015), (Table 5). The moderate and severe forms of AD are recorded significantly more often in patients suffering from food hypersensitivity reactions as mentioned above (Table 2); these patients suffer as well significantly more often from allergic rhinitis and persistent eczematic lesions.…”

“…The moderate and severe forms of AD are recorded significantly more often in patients suffering from food hypersensitivity reactions as mentioned above (Table 2); these patients suffer as well significantly more often from allergic rhinitis and persistent eczematic lesions. Patients with reactions to nuts suffer more often from bronchial asthma and allergic rhinitis; the reaction to kiwi and fish is recorded more often in patients with persistent eczematic lesions, and reaction to apples is recorded more often in patients with allergic rhinitis (Celakovska, Bukac, & Ettler, 2015).…”

“…We have created a unique group of patients, in which the different parameters concerning atopic march in 172-301 patients were studied. The detailed description of these studies is recorded in our previous publications (Celakovska, Bukac, & Ettler, 2015;Celakovska, Ettlerova, Ettler, Vaněčková, & Bukač, 2015;Celakovska & Bukac, 2015a, 2015b, 2016a, 2016b, 2017a, 2017bČelakovská, Krčmová, Bukač, & Vaněčková, 2017;Vaneckova & Bukac, 2016. All these patients were examined in the Department of Dermatology, Faculty Hospital Hradec Králové, Charles University of Prague, Czech Republic.…”