The effect of various substances on the composition and quality of wine has been studied. Only imazalil residue was 0.35 µg/ dm 3 , in course of use the activated coal in a dose of 300 mg/dm 3 and no other pesticides were found. The pesticide residue was totally over during the next use of doses (450 & 600 mg/dm 3 ) of the activated coal. So, the dose of activated coal of 450 mg/ dm 3 is sufficient to remove totally the residue of pesticide out of wine examples. The more significant dose of bentonite was 600 mg/dm 3 . In this case, the most affected one was imazalil. İncreasing the dose of casein from 150 mg/dm 3 up to 600 mg/ dm 3 is observed decreasing with about 5-10 times of the different pesticide residue but these doses weren`t enough to remove the pesticide totally/ we can see show α-endosulfan (about 10 times) and pencondzolen (about 6 times) among highly affected pesticide residues. The weakest effect was PVPP and the strongest one was attributed to activated coal during the removing process of pesticides residues by diluents.