Food sensitivity in reflux oesophagitis

Price, Steven F.; Smithson, Kenneth W.; Castell, Donald O.

doi:10.1007/978-94-017-4389-1_48

Cited by 6 publications

(6 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…While these beverages are acidic, they may contribute to heartburn in other ways. Bernstein test-positive patients were still highly sensitive to intraoesophageal infusions of orange juice even after the pH was adjusted to 7, suggesting that they are not just sensitive to a low pH [Price et al 1978]. Citrus drinks did not reduce LOS pressure in patients with heartburn and actually increased pressure in asymptomatic controls [Cranley et al 1986].…”

Section: Dietmentioning

confidence: 99%

Lifestyle measures in the management of gastro-oesophageal reflux disease: clinical and pathophysiological considerations

Kang

2015

Therapeutic Advances in Chronic Disease

View full text Add to dashboard Cite

Several lifestyle and dietary factors are commonly cited as risk factors for gastrooesophageal reflux disease (GORD) and modification of these factors has been advocated as first-line measures for the management of GORD. We performed a systematic review of the literature from 2005 to the present relating to the effect of these factors and their modification on GORD symptoms, physiological parameters of reflux as well as endoscopic appearances. Conflicting results existed for the association between smoking, alcohol and various dietary factors in the development of GORD. These equivocal findings are partly due to methodology problems. There is recent good evidence that weight reduction and smoking cessation are beneficial in reducing GORD symptoms. Clinical and physiological studies also suggest that some physical measures as well as modification of meal size and timing can also be beneficial. However, there is limited evidence for the role of avoiding alcohol and certain dietary ingredients including carbonated drinks, caffeine, fat, spicy foods, chocolate and mint.

show abstract

Section: Dietmentioning

confidence: 99%

Lifestyle measures in the management of gastro-oesophageal reflux disease: clinical and pathophysiological considerations

Kang

2015

Therapeutic Advances in Chronic Disease

View full text Add to dashboard Cite

show abstract

“…osmolality and fat content, [15][16][17] smoking, [18][19][20][21][22] emotional factors 23 and visceral hypersensitivity. 15,16 This latter feature is considered a biological marker of the irritable bowel syndrome (IBS), 24 a condition associated with GERD.…”

Section: Introductionmentioning

confidence: 99%

“…15,16 This latter feature is considered a biological marker of the irritable bowel syndrome (IBS), 24 a condition associated with GERD. 2,25,26 In as much as the basic pathophysiological mechanism in GERD is exposure of the oesophageal mucosa to the noxious effect of acid, and since acid exposure accounts for only a minor fraction of the variation in GERD symptoms, the relationship between OAE and GERD symptoms might be modulated by additional factors were hypothesized.…”

Section: Introductionmentioning

confidence: 99%

Irritable bowel, smoking and oesophageal acid exposure: an insight into the nature of symptoms of gastro‐oesophageal reflux

Zimmerman¹

2004

Aliment Pharmacol Ther

View full text Add to dashboard Cite

Summary Background : In gastro‐oesophageal reflux disease, oesophageal acid exposure correlates with symptoms but explains only a small fraction of their variance. Aims : To elucidate the effects of irritable bowel syndrome and smoking on gastro‐oesophageal reflux disease symptoms and to clarify whether they modulate the relationship between oesophageal acid exposure and symptoms. Methods : The relationship between oesophageal acid exposure, irritable bowel syndrome (Rome I criteria), smoking status and symptoms was investigated in patients with a normal gastroscopy who underwent a 24‐h oesophageal pH monitoring. Results : Of 256 patients with gastro‐oesophageal reflux disease, 16% were smokers and 50% met the criteria for irritable bowel syndrome (irritable bowel syndrome+). The extent of oesophageal acid exposure was unrelated to smoking or irritable bowel syndrome status. Oesophageal acid exposure, irritable bowel syndrome status and current smoking independently predicted symptoms. Irritable bowel syndrome and smoking modulated the effect of oesophageal acid exposure on symptoms: oesophageal acid exposure was predictive of symptoms only in non‐smokers. However, irritable bowel syndrome was a significant predictor of symptoms both in smokers and in non‐smokers. Smoking was associated with symptoms only in irritable bowel syndrome+, while oesophageal acid exposure was associated with symptoms irrespective of irritable bowel syndrome status. Conclusions : In patients with non‐erosive gastro‐oesophageal reflux disease, smoking and irritable bowel syndrome independently predicted symptoms, without affecting the extent of oesophageal acid exposure. The relationship between oesophageal acid exposure and symptoms was affected significantly, and in opposite directions, by smoking and irritable bowel syndrome.

show abstract

“…These measures include reducing excessive body weight, avoiding intake of reflux‐inducing foods or substances (e.g. greasy and spicy foods, tomatoes, highly acidic citrus products and carbonated drinks) and reducing alcohol intake, 7–10 although considerable variation exists with respect to the sensitivity of individuals to foods or substances that may induce reflux.…”

Section: Initial Therapymentioning

confidence: 99%

Contemporary understanding and management of reflux and constipation in the general population and pregnancy: a consensus meeting

Tytgat

Heading

Müller-Lissner

et al. 2003

Aliment Pharmacol Ther

View full text Add to dashboard Cite

Summary Background : Gastro‐oesophageal reflux disease (GERD) and constipation have a major impact on public health; however, the wide variety of treatment options presents difficulties for recommending therapy. Lack of definitive guidelines in pharmacy and general practice medicine further exacerbates the decision dilemma. Aims : To address these issues, a panel of experts discussed the principles and practice of treating GERD and constipation in the general population and in pregnancy, with the aim of developing respective treatment guidelines. Results : The panel recommended antacids ‘on‐demand’ as the first‐line over‐the‐counter treatment in reflux, and as rescue medication for immediate relief when reflux breaks through with proton pump inhibitors. Calcium/magnesium‐based antacids were recommended as the treatment of choice for pregnant women because of their good safety profile. In constipation, current data do not distinguish a hierarchy between polyethylene glycol (PEG)‐based laxatives and other first‐line treatments, although limitations are associated with stimulant‐ and bulk‐forming laxatives. Where data are available, PEG is superior to lactulose in terms of efficacy. In pregnancy, PEG‐based laxatives meet the criteria for the ideal treatment. Conclusions : The experts developed algorithms that present healthcare professionals with clear treatment options and management strategies for GERD and constipation in pharmacy and general practice medicine.

show abstract

Food sensitivity in reflux oesophagitis

Cited by 6 publications

References 8 publications

Lifestyle measures in the management of gastro-oesophageal reflux disease: clinical and pathophysiological considerations

Lifestyle measures in the management of gastro-oesophageal reflux disease: clinical and pathophysiological considerations

Irritable bowel, smoking and oesophageal acid exposure: an insight into the nature of symptoms of gastro‐oesophageal reflux

Contemporary understanding and management of reflux and constipation in the general population and pregnancy: a consensus meeting

Contact Info

Product

Resources

About